NMJ Blockers Flashcards
(16 cards)
Structure of NMJ blockers
Analogs of Ach
What are the NMJ blockers
Tubocurarine
Succinylcholine
Which NMJ blocker is non-depolarizing
Tubucurarine
Which NMJ blocker is depolarizing
Succinylcholine
What receptor do NMJ blockers bind
Nm
What kind of paralysis do NMJ blockers cause
Flaccid
What is Tubocurarine used for
Anesthesia
What is Succinylcholine used for
ET tubation
ECT
What counteracts Tubocurarine
Neostigmine
Edrophonium
Mode of administration of Tubocurarine
IV
Mode of administration of Succinylcholine
IV
Which NMJ blocker may bind M receptors and cause histamine release
Tubocurarine
Which NMJ blocker may cause malignant hyperthermia
Succinylcholine, when combined with halogenated anesthetic
Tx for malignant hyperthermia
Dantrolene
Does tubocurarine cross the BBB
No
How would you describe the duration of succinylcholine activity
Fast - Onset, duration
