Indirect Adrenergic Agonists Flashcards Preview

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Flashcards in Indirect Adrenergic Agonists Deck (9)
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1

What causes serious vasopressor episodes in pts on MAOIs after release of NE

Tyramine

2

What is the mechanism of Amphetamine

Displace catecholamine from storage vesicle
Weak MAOI
Block catecholamine reuptake

3

Effects of Amphetamine

Increase BP (alpha 1, beta)
Stimulation (alertness, decrease appetite, insomnia)

4

What is Amphetamine used as a Tx for

Depression
Narcolepsy

5

What is the Tx for ADHD in children

Methylphenidate (amphetamine analog)

6

Where is Tyramine found

Cheese
Wine

7

What oxidizes Tyramine

MAO

8

AE of Amphetamine

Fatigue/Depression after stimulation

9

Common feature of all indirect acting adrenergic agonists

Potentiate NE action by causing release