Uworld Exam 11 Flashcards Preview

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Flashcards in Uworld Exam 11 Deck (52):
1

MC pituitary adenoma in a child?

craniopharyngioma

2

Anterior pituitary origin?

Rathke's pouch

3

Posterior pituitary origin?

neuroectoderm

4

Craniopharyngioma contains 3 components?

Solid, cystic, calcification

5

Another word for urge incontinence? MOA?

Gotta Go!
MOA: destrusor muscle instability (overactive bladder)

6

A patient who has an urge to urinate and cannot make it to the bathroom and pees on herself? Tx?

urge incontinence
Tx: Antimuscarinics

7

Tricuspid valve is heard best at?

4th ICS at the lower sternal border (parasternal)

8

Synthesis of multiple, short DNA fragments?

Okazaki Fragments

9

A patient with Excessive Daytime Sleepiness and Laughter/crying triggers paralysis. Dx? What is undetectable/low in the CSF of this patient?

Narcolepsy
CSF: Hypocretin-1

10

Where is Hypocretin made and what does it do?

Location: Lateral hypothalamus
Function: promote wakefulness and inhibit REM sleep

11

A patient feels that the physician resembles his dad in that he was not there for him. Dx?

Transference

12

Occurrence of multiple phenotypes often in different organ systems as a result of a single genetic defect?

Pleiotropy

13

Proportion of individuals who express the associated phenotype

Penetrance

14

Hib vaccine is composed of what? What is it attached to?

capsular polysaccharide
Diptheria/Tetanus

15

Haemophilus inflenzae type b causes what particular disease?

meninigitis

16

Obstructive sleep apnea can lead to what two manifestations?

Pul. HTN and R. Heart Failure

17

Pulsatile Treatment of GnRH is for?

Infertility

18

Most Hypoosmolar in the nephron?

Early Distal Tubule

19

Aortic Regurgitation Murmur is best heard where?

Left Sternal Border, patient leaning forward and on expiration

20

Liver Biopsy shows pigmented inclusions in the lysosomes and the pigments are polymers of epinephrine. What disease?

Dubin Johnson

21

Dubin Johnson pathogenesis?

defective hepatocellular excretion of bilirubin glucuronides

22

1 standard deviation equals?

68%

23

During a urine deprivation test, a primary polydipsic patient will exhibit what kind of urine osmolarity?

significant increase in urine osmolality

24

Sublingual Table for Angina?

Nitrates

25

What Ig crosses placenta?

IgG

26

Down Syndrome Disjunction?

Nondisjunction in maternal meiosis I

27

Glucocorticoid therapy can lead to entire shunt down of the HPA axis which can lead to?

adrenal insufficiency (MC)

28

Eosinophils two MOA?

1. Parasite: IL-5 via Th2 to parasites, major basic protein and ADCC
2. Type 1 HSR cytokine production

29

Mucicarmine stain is used to detect?

C. Neoformans

30

Cryptococcus most common presentation?

meningoencephalitis

31

PABA esters are used to absorb?

UVB

32

1st line for depression?

SSRI

33

Precursor of serotonin?

tryptophan

34

Antidote to serotonin syndrome?

Cyproheptadine

35

VZV lacks what kinase?

thymidine kinase

36

A large mass after a tooth extraction?

Actinomyces israelii

37

Tx for actinomyces israelii?

Penicillin

38

Apical Lung Tumors called? What syndrome can they produce?

Pancoast Tumors
Horner's Syndrome

39

A patient with pain is given an opioid and it causes a abdominal pain. What is this called?

Biliary Colic=>constriction of sphincter of oddi

40

Tet Spells are seen in patients with?

Right to Left Shunts

41

Preeclampisa has what three things?

HTN, Proteinuria, edema

42

MC thyroid cancer?

Papillary thyroid Cancer

43

Bx shows large cells with nuclei containing finely dispersed chromatin with ground glass appearance. What is this and where is it found?

Orphan Anne Eyes
Found in Papillary thyroid cancer

44

Septic Arthritis Prophylaxis while waiting for results?

Ceftriaxone

45

Bilateral renal agenesis leads to?

Potter's Syndrome

46

What do potter's syndrome patients most often die of?

Lung Immaturity

47

Epidural hematoma is found between?

Bone and dura mater

48

Epidural hematoma CT?

Biconvex, Lens

49

Subdural Hematoma CT?

Crescent shaped

50

Subarachnoid CT?

Blood in basal cisterns

51

Hashimoto Thyroiditis Bx?

Mononuclear, parenchymal infiltration with well developed germinal centers

52

Serotonin Syndrome symptoms?

After treatment with a SSRI or SNRI, you get myoclonus, flushing, diarrhea