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Uworld > Uworld Exam 11 > Flashcards

Uworld Exam 11 Flashcards

1
Q

MC pituitary adenoma in a child?

A

craniopharyngioma

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2
Q

Anterior pituitary origin?

A

Rathke’s pouch

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3
Q

Posterior pituitary origin?

A

neuroectoderm

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4
Q

Craniopharyngioma contains 3 components?

A

Solid, cystic, calcification

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5
Q

Another word for urge incontinence? MOA?

A

Gotta Go!

MOA: destrusor muscle instability (overactive bladder)

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6
Q

A patient who has an urge to urinate and cannot make it to the bathroom and pees on herself? Tx?

A

urge incontinence

Tx: Antimuscarinics

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7
Q

Tricuspid valve is heard best at?

A

4th ICS at the lower sternal border (parasternal)

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8
Q

Synthesis of multiple, short DNA fragments?

A

Okazaki Fragments

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9
Q

A patient with Excessive Daytime Sleepiness and Laughter/crying triggers paralysis. Dx? What is undetectable/low in the CSF of this patient?

A

Narcolepsy

CSF: Hypocretin-1

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10
Q

Where is Hypocretin made and what does it do?

A

Location: Lateral hypothalamus
Function: promote wakefulness and inhibit REM sleep

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11
Q

A patient feels that the physician resembles his dad in that he was not there for him. Dx?

A

Transference

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12
Q

Occurrence of multiple phenotypes often in different organ systems as a result of a single genetic defect?

A

Pleiotropy

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13
Q

Proportion of individuals who express the associated phenotype

A

Penetrance

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14
Q

Hib vaccine is composed of what? What is it attached to?

A

capsular polysaccharide

Diptheria/Tetanus

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15
Q

Haemophilus inflenzae type b causes what particular disease?

A

meninigitis

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16
Q

Obstructive sleep apnea can lead to what two manifestations?

A

Pul. HTN and R. Heart Failure

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17
Q

Pulsatile Treatment of GnRH is for?

A

Infertility

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18
Q

Most Hypoosmolar in the nephron?

A

Early Distal Tubule

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19
Q

Aortic Regurgitation Murmur is best heard where?

A

Left Sternal Border, patient leaning forward and on expiration

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20
Q

Liver Biopsy shows pigmented inclusions in the lysosomes and the pigments are polymers of epinephrine. What disease?

A

Dubin Johnson

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21
Q

Dubin Johnson pathogenesis?

A

defective hepatocellular excretion of bilirubin glucuronides

22
Q

1 standard deviation equals?

A

68%

23
Q

During a urine deprivation test, a primary polydipsic patient will exhibit what kind of urine osmolarity?

A

significant increase in urine osmolality

24
Q

Sublingual Table for Angina?

A

Nitrates

25
Q

What Ig crosses placenta?

A

IgG

26
Q

Down Syndrome Disjunction?

A

Nondisjunction in maternal meiosis I

27
Q

Glucocorticoid therapy can lead to entire shunt down of the HPA axis which can lead to?

A

adrenal insufficiency (MC)

28
Q

Eosinophils two MOA?

A
  1. Parasite: IL-5 via Th2 to parasites, major basic protein and ADCC
  2. Type 1 HSR cytokine production
29
Q

Mucicarmine stain is used to detect?

A

C. Neoformans

30
Q

Cryptococcus most common presentation?

A

meningoencephalitis

31
Q

PABA esters are used to absorb?

A

UVB

32
Q

1st line for depression?

A

SSRI

33
Q

Precursor of serotonin?

A

tryptophan

34
Q

Antidote to serotonin syndrome?

A

Cyproheptadine

35
Q

VZV lacks what kinase?

A

thymidine kinase

36
Q

A large mass after a tooth extraction?

A

Actinomyces israelii

37
Q

Tx for actinomyces israelii?

A

Penicillin

38
Q

Apical Lung Tumors called? What syndrome can they produce?

A

Pancoast Tumors

Horner’s Syndrome

39
Q

A patient with pain is given an opioid and it causes a abdominal pain. What is this called?

A

Biliary Colic=>constriction of sphincter of oddi

40
Q

Tet Spells are seen in patients with?

A

Right to Left Shunts

41
Q

Preeclampisa has what three things?

A

HTN, Proteinuria, edema

42
Q

MC thyroid cancer?

A

Papillary thyroid Cancer

43
Q

Bx shows large cells with nuclei containing finely dispersed chromatin with ground glass appearance. What is this and where is it found?

A

Orphan Anne Eyes

Found in Papillary thyroid cancer

44
Q

Septic Arthritis Prophylaxis while waiting for results?

A

Ceftriaxone

45
Q

Bilateral renal agenesis leads to?

A

Potter’s Syndrome

46
Q

What do potter’s syndrome patients most often die of?

A

Lung Immaturity

47
Q

Epidural hematoma is found between?

A

Bone and dura mater

48
Q

Epidural hematoma CT?

A

Biconvex, Lens

49
Q

Subdural Hematoma CT?

A

Crescent shaped

50
Q

Subarachnoid CT?

A

Blood in basal cisterns

51
Q

Hashimoto Thyroiditis Bx?

A

Mononuclear, parenchymal infiltration with well developed germinal centers

52
Q

Serotonin Syndrome symptoms?

A

After treatment with a SSRI or SNRI, you get myoclonus, flushing, diarrhea

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