Uworld Practice Test 1 Flashcards

1
Q

ARDS is caused by injury to?

A

Endothelial Lining

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2
Q

Paget’s disease of the bone is associated with?

A

Osteosarcoma

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3
Q

Lump in the throat is?

A

Globus hystericus

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4
Q

What vitamin is tetratogenic?

A

vitamin A

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5
Q

Oseltamivir (Tamiflu) MOA? Use?

A

MOA: inhibits neuroamindase of influenza A and B
Use: Early treatment and prevention of influenza

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6
Q

Cells varying in length and time show?

A

Posttranslational modification

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7
Q

Fragmentation in multiples of 180 base pairs. What is this called?

A

DNA Laddering

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8
Q

Where is DNA laddering found?

A

During Karrhyrexis in Apoptotic cells

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9
Q

Why is DNA laddering used?

A

To distinguish between apoptotic cells and necrotic cells

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10
Q

Physgiostigimine fights?

A

Atropine

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11
Q

Benzodiazpine AE?

A

confusion

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12
Q

When a genetic mutation is identified in the offspring but not the parents?

A

Germline Mosaicism

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13
Q

DM patients should always do what every day?

A

Foot Ulcer

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14
Q

IL-1, TNF-alpha, IL-6 is primarily produced by? What are they produced in response to?

A

Mononuclear phagocytes/Marcrophages

Inflammation

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15
Q

What is Ca2+ dependent and connects intercellular adhesions?

A

Cadherins

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16
Q

Low pH of udodenal content triggers release of?

A

Bicarb

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17
Q

Posterior displacement of the tibia? What artery is affected?

A

popliteal artery

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18
Q

Foul Smelling Discharge after a vaginal delivery? Agent?

A

Endometritis

Bacteriodes

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19
Q

Person channels socially unacceptable impulses to acceptable impulses (like channeling abuse to basketball)

A

Sublimation

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20
Q

Tyrosine Kinase auto?

A

phosphorylates and dimerizes

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21
Q

Physician repeats what patient has told him? Defense mechanism?

A

Reflection

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22
Q

Physician encourages patient to talk more about a technique?

A

facilitation

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23
Q

Individual attributes thoughts and feelings to another person

A

projection

24
Q

Headache, chronic nasal discharge and atrophic septum?

A

Cocaine absuer

25
Q

Heminephrectomy changes GFR from what to what?

A

50%=>80%

26
Q

When she pushes against a wall with outstreched arms, there is prominence of the right scapular angle? What nerve and muscle is involved?

A

Winged Scapula
SALT
(serratus anterior and Long thoracic n.)

27
Q

ATSD vs PTSD Difference?

A

> 4 weeks PTSD

28
Q

Schizophrenia symptoms?

A

Delusions, hallucinations, disorganized speech or negative symptoms

29
Q

Schizophrenic symptoms for 1-6 months

A

Schizophreniform symptoms

30
Q

Schizophrenic symptoms for >6 months

A

Schizophrenia

31
Q

Schizophrenic symptoms

A

Brief Psychotic episodes

32
Q

Relative Risk?

A

Exposed Risk/Unexposed Risk

33
Q

Number needed to treat is opposite of the?

A

absolute risk reduction value

34
Q

Absolute Risk Reduction?

A

Percentage of mortality in Conventional-Percentage of mortality in Novel

35
Q

Headache, altered level of consciousness and increased signalling in the temporal lobe?

A

Encephalitis

36
Q

MCC of viral Encephalitis?

A

HSV

37
Q

MC Porphyria?

A

Porphyria cutanea tarda

38
Q

Acute Intermittent Porphyria, enzyme and accumulation?

A

Hydroxymethylbilane (HMB) synthase

Porphobilinogen

39
Q

Porphyria Cutanea Tarda, enzyme and accumulation?

A

URO decarboxylase

Uroporphyrinogen

40
Q

What diseases have Anticipation?

A

Trinucleotide repeat diseases

41
Q

Recurrent hemathroses?

A

Hemophilia

42
Q

Hemophilia Genetics?

A

X-linked

43
Q

Exudate vs transudate fluid

A

Exudate

Protein>0.5 and Pleural LDH>0.6

44
Q

Hemolysis in buffered salt solutions?

A

Osmotic Fragility

45
Q

Hereditary Sphercytosis Labs?

A

Increased MCHC, acidified glycerol test

abnormal eosin 5

46
Q

Complications of hereditary sphercytosis

A

Gallstones and aplastic anemia

47
Q

An elderly alcholic with Shock-like sensation that radiates to the feet and neck, what vitamin def.?

A

B12

48
Q

B12 vs Folate deficiency?

A

Folate does not induce neurologic symptoms

49
Q

A young patient with difficulty chewing, seeing, What is wrong in this patient?

A

MG

50
Q

Which is more common Hyperplastic Tissue vs Thymoma?

A

Hyperplastic Tissue

51
Q

How many genes need to deleted in tumor supressor genes? What is this phenomenon called? Examples?

A

2
2 hit hypothesis
Retinoblastoma

52
Q

Recurrent Fungal or Viral infections suggest problems in?

A

T-Cell lymphocyte

53
Q

Digeorge Syndrome is the failure of the development of?

A

3rd and 4th pouch

54
Q

Metabolics associated with DKA?

A

Metabolic Acidosis, Hyperkalemia, Hyperglycemia, Hyperammoniemia, Hyponatremia

55
Q

In pheochromocytoma, what drug should you use?

A

Phenoxybenzamine