Uworld Practice Test 1 Flashcards Preview

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Flashcards in Uworld Practice Test 1 Deck (55):
1

ARDS is caused by injury to?

Endothelial Lining

2

Paget's disease of the bone is associated with?

Osteosarcoma

3

Lump in the throat is?

Globus hystericus

4

What vitamin is tetratogenic?

vitamin A

5

Oseltamivir (Tamiflu) MOA? Use?

MOA: inhibits neuroamindase of influenza A and B
Use: Early treatment and prevention of influenza

6

Cells varying in length and time show?

Posttranslational modification

7

Fragmentation in multiples of 180 base pairs. What is this called?

DNA Laddering

8

Where is DNA laddering found?

During Karrhyrexis in Apoptotic cells

9

Why is DNA laddering used?

To distinguish between apoptotic cells and necrotic cells

10

Physgiostigimine fights?

Atropine

11

Benzodiazpine AE?

confusion

12

When a genetic mutation is identified in the offspring but not the parents?

Germline Mosaicism

13

DM patients should always do what every day?

Foot Ulcer

14

IL-1, TNF-alpha, IL-6 is primarily produced by? What are they produced in response to?

Mononuclear phagocytes/Marcrophages
Inflammation

15

What is Ca2+ dependent and connects intercellular adhesions?

Cadherins

16

Low pH of udodenal content triggers release of?

Bicarb

17

Posterior displacement of the tibia? What artery is affected?

popliteal artery

18

Foul Smelling Discharge after a vaginal delivery? Agent?

Endometritis
Bacteriodes

19

Person channels socially unacceptable impulses to acceptable impulses (like channeling abuse to basketball)

Sublimation

20

Tyrosine Kinase auto?

phosphorylates and dimerizes

21

Physician repeats what patient has told him? Defense mechanism?

Reflection

22

Physician encourages patient to talk more about a technique?

facilitation

23

Individual attributes thoughts and feelings to another person

projection

24

Headache, chronic nasal discharge and atrophic septum?

Cocaine absuer

25

Heminephrectomy changes GFR from what to what?

50%=>80%

26

When she pushes against a wall with outstreched arms, there is prominence of the right scapular angle? What nerve and muscle is involved?

Winged Scapula
SALT
(serratus anterior and Long thoracic n.)

27

ATSD vs PTSD Difference?

>4 weeks PTSD

28

Schizophrenia symptoms?

Delusions, hallucinations, disorganized speech or negative symptoms

29

Schizophrenic symptoms for 1-6 months

Schizophreniform symptoms

30

Schizophrenic symptoms for >6 months

Schizophrenia

31

Schizophrenic symptoms

Brief Psychotic episodes

32

Relative Risk?

Exposed Risk/Unexposed Risk

33

Number needed to treat is opposite of the?

absolute risk reduction value

34

Absolute Risk Reduction?

Percentage of mortality in Conventional-Percentage of mortality in Novel

35

Headache, altered level of consciousness and increased signalling in the temporal lobe?

Encephalitis

36

MCC of viral Encephalitis?

HSV

37

MC Porphyria?

Porphyria cutanea tarda

38

Acute Intermittent Porphyria, enzyme and accumulation?

Hydroxymethylbilane (HMB) synthase
Porphobilinogen

39

Porphyria Cutanea Tarda, enzyme and accumulation?

URO decarboxylase
Uroporphyrinogen

40

What diseases have Anticipation?

Trinucleotide repeat diseases

41

Recurrent hemathroses?

Hemophilia

42

Hemophilia Genetics?

X-linked

43

Exudate vs transudate fluid

Exudate
Protein>0.5 and Pleural LDH>0.6

44

Hemolysis in buffered salt solutions?

Osmotic Fragility

45

Hereditary Sphercytosis Labs?

Increased MCHC, acidified glycerol test
abnormal eosin 5

46

Complications of hereditary sphercytosis

Gallstones and aplastic anemia

47

An elderly alcholic with Shock-like sensation that radiates to the feet and neck, what vitamin def.?

B12

48

B12 vs Folate deficiency?

Folate does not induce neurologic symptoms

49

A young patient with difficulty chewing, seeing, What is wrong in this patient?

MG

50

Which is more common Hyperplastic Tissue vs Thymoma?

Hyperplastic Tissue

51

How many genes need to deleted in tumor supressor genes? What is this phenomenon called? Examples?

2
2 hit hypothesis
Retinoblastoma

52

Recurrent Fungal or Viral infections suggest problems in?

T-Cell lymphocyte

53

Digeorge Syndrome is the failure of the development of?

3rd and 4th pouch

54

Metabolics associated with DKA?

Metabolic Acidosis, Hyperkalemia, Hyperglycemia, Hyperammoniemia, Hyponatremia

55

In pheochromocytoma, what drug should you use?

Phenoxybenzamine