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Uworld > Uworld Exam 7 > Flashcards

Uworld Exam 7 Flashcards

1
Q

Ether inactivates what kind of viruses?

A

enveloped

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2
Q

After Ovulation, Secondary Oocyte is in what phase?

A

M2

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3
Q

Different protein isoforms are created by?

A

Alternate RNA Gene Splicing

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4
Q

An electrical wave by passing the AV node will change?

A

PR Interval

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5
Q

WPW shows a triad. What are the Triad of electrical symptoms?

A

Shortened PR interval, a delta wave in QRS, widened QRS complex

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6
Q

Th0=>induced to Th1 by?

A

IFN-gamma, and IL-12

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7
Q

Th0=>induced to Th2 by?

A

IL-4

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8
Q

Disulfiram Like Drugs?

A

Metronidazole, Griseofulvin, procarbazine and sulfonylureas

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9
Q

When patient is unconscious, do you tell a family member about the condition?

A

Yes, Share the information if it is in the best interest of the patient

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10
Q

Sensitivity identifies those with the disease? Yes or No?

A

Yes

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11
Q

Methylated DNA and Acetylated DNA, what is the difference?

A

Methylated DNA mutes

Acetylated DNA activates

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12
Q

SCLC marker?

A

Neuroendocrine origin=>Neurofilaments: enolase, chromogranin, synaptophysin

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13
Q

Antidepressants Increase the risk for?

A

Inducing Mania

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14
Q

Diffuse Gallbladder Calcifications; What should you do?

A

Porcelain gallbladder=>chronic cholecystitis; prophylatically remove due to increase risk of gallbladder cancer

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15
Q

In Alzheimer’s Disease, what hydrocephalus do you see?

A

Hydrocephalus ex vacuo

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16
Q

Oral Thrush on Tongue Tx?

A

Nystatin

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17
Q

V/Q increased or decreased in apex and base?

A

Apex=>V/Q increases

Base=>V/Q decreases

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18
Q

What pleura is for pain? And what nerves carry it?

A

Parietal Pleura, Phrenic Nerve

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19
Q

Streptomycin MOA?

A

MOA: Binds to 30S ribosomal unit and blocks initiation of protein synthesis

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20
Q

As you age what proteins do you lose?

A

Collagen and elastin

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21
Q

Which cell CANNOT use Ketone bodies for energy?

A

erythrocytes

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22
Q

Central Regulator of Iron homeostasis? MOA of regulation?

A

Hepicidin

MOA: Binds to Ferroportin and degrades it=>decreases iron absorption and does not allow macrophages to release iron

23
Q

Hepcidin increased in? Decreased? In what disease do you associate this with?

A

High Iron levels and inflammation increase levels
Hypoxia and erythropoiesis act to decrease levels
Anemia of Chronic Disease

24
Q

Does Health care proxy overrule all?

A

Yes

25
Q

Benzodiazepines MOA?

A

MOA: binds on allosteric site of GABAa=>increasing frequency (ion channel frequency); Ben Likes it more often, Barb likes it longer

26
Q

Baclofen MOA?

A

MOA: activates GABAb receptor=>G protein

27
Q

Two drugs that alter GABA metabolism?

A

Valproic acid and vigabetin=>reduce catabolism (reduce breakdown)

28
Q

Paroxsymal supraventricular tachycardia (PSVT) MOA? and epidemology?

A

MOA: re-entry impulse via slow and fast fibers

MC paroxsymal supraventricular tachycardia

29
Q

Carotid sinuses are innervated by what nerve?

A

CN 9

30
Q

Carotid Sinus Massage does what to the baroreceptor firing and what is the result?

A

Increases firing (hering nerve) and parasymp. influence prolongs AV refractory period

31
Q

Woman with Osteoporosis and HTN? Why?

A

HCTZ; increases Calcium (HyperGLUC)

32
Q

1st generation Antihistamines are?

A

Diphenhydramine, Dimenhydrinate, chlorpheniramine and promethazine
Amine, nate, azine

33
Q

2nd generation Antihistamines are

A

Loratadine, fexofenadine, desloratadine and cetirizine

-adine or izine

34
Q

VZV histology?

A

Bx: Multinucleated inclusion-bearing giant cells

35
Q

Anabolic steriods (methyltestosterone) can lead to?

A

Acne

36
Q

What differentiates between Direct and Indirect Inguinal Hernia?

A

Inferior epigastric vessels

37
Q

Prostacyclins do what?

A

inhibit platelet aggregation

38
Q

HBV helps HDV (delta agent) in what way?

A

Delta agent is coated with HBsAg to get into cells

39
Q

With Chronic Lung Rejection, where do the immune rxn affect?

A

small airways

40
Q

What cytokine moves Smooth Muscle Cells from the Media to Intima? Who secretes it? What does it do?

A

PDGF and platelets;

migrates SMC from media to intima and proliferate in the intima

41
Q

Platelets secrete TGF-B. What does it do?

A

Smooth muscle cell chemotaxis and interstitial collagen production

42
Q

Lissencephaly results in? What do you see in MRI?

A

Results in: congenital absence of gyri

MRI: smooth brain

43
Q

Pseudotumor Cerebri what is the problem? What does it lead to?

A

Increased ICP with normal CSF and normal neuroimaging, optic nerve atrophy and blindness

44
Q

Spherules packed in spores

A

Coccidiodides immitis

45
Q

DM neuropathy is associated with?

A

Endoneural arteriole hyalinization

46
Q

Small Erythematous papules on the palms with excoriations, scattered vesicles and pustules on the finger webs, palms and wrist creases

A

Scabies mite and eggs

47
Q

Coffee Ground Color Indicates?

A

That the bleeding has touched acid=>oxidation of heme

48
Q

Increases in Preload do what to sarcomere length?

A

Increase

49
Q

Cleft Lip and palate, polydactyly, rockerbottom feet, holoprosencephaly

A

Trisomy 13

50
Q

Trisomy 13 Cause?

A

Meiosis I Non disjunction

51
Q

Coughing or Sneezing=>urine coming out; what kind of dysfunction is it?

A

Stress Urinary Incontinence=>Urethral Sphincter dysfunction

52
Q

Sudden Overwhelming Need to empty bladder; What kind of dysfunction is it?

A

Urge Incontinence=>Detrussor overactivity

53
Q

Constant involuntary dripping; What kind of dysfunction is it?

A

Overflow incontinence=>impair detrussor contractility

Uworld (27 decks)

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