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Flashcards in Uworld Exam 7 Deck (53):
1

Ether inactivates what kind of viruses?

enveloped

2

After Ovulation, Secondary Oocyte is in what phase?

M2

3

Different protein isoforms are created by?

Alternate RNA Gene Splicing

4

An electrical wave by passing the AV node will change?

PR Interval

5

WPW shows a triad. What are the Triad of electrical symptoms?

Shortened PR interval, a delta wave in QRS, widened QRS complex

6

Th0=>induced to Th1 by?

IFN-gamma, and IL-12

7

Th0=>induced to Th2 by?

IL-4

8

Disulfiram Like Drugs?

Metronidazole, Griseofulvin, procarbazine and sulfonylureas

9

When patient is unconscious, do you tell a family member about the condition?

Yes, Share the information if it is in the best interest of the patient

10

Sensitivity identifies those with the disease? Yes or No?

Yes

11

Methylated DNA and Acetylated DNA, what is the difference?

Methylated DNA mutes
Acetylated DNA activates

12

SCLC marker?

Neuroendocrine origin=>Neurofilaments: enolase, chromogranin, synaptophysin

13

Antidepressants Increase the risk for?

Inducing Mania

14

Diffuse Gallbladder Calcifications; What should you do?

Porcelain gallbladder=>chronic cholecystitis; prophylatically remove due to increase risk of gallbladder cancer

15

In Alzheimer's Disease, what hydrocephalus do you see?

Hydrocephalus ex vacuo

16

Oral Thrush on Tongue Tx?

Nystatin

17

V/Q increased or decreased in apex and base?

Apex=>V/Q increases
Base=>V/Q decreases

18

What pleura is for pain? And what nerves carry it?

Parietal Pleura, Phrenic Nerve

19

Streptomycin MOA?

MOA: Binds to 30S ribosomal unit and blocks initiation of protein synthesis

20

As you age what proteins do you lose?

Collagen and elastin

21

Which cell CANNOT use Ketone bodies for energy?

erythrocytes

22

Central Regulator of Iron homeostasis? MOA of regulation?

Hepicidin
MOA: Binds to Ferroportin and degrades it=>decreases iron absorption and does not allow macrophages to release iron

23

Hepcidin increased in? Decreased? In what disease do you associate this with?

High Iron levels and inflammation increase levels
Hypoxia and erythropoiesis act to decrease levels
Anemia of Chronic Disease

24

Does Health care proxy overrule all?

Yes

25

Benzodiazepines MOA?

MOA: binds on allosteric site of GABAa=>increasing frequency (ion channel frequency); Ben Likes it more often, Barb likes it longer

26

Baclofen MOA?

MOA: activates GABAb receptor=>G protein

27

Two drugs that alter GABA metabolism?

Valproic acid and vigabetin=>reduce catabolism (reduce breakdown)

28

Paroxsymal supraventricular tachycardia (PSVT) MOA? and epidemology?

MOA: re-entry impulse via slow and fast fibers
MC paroxsymal supraventricular tachycardia

29

Carotid sinuses are innervated by what nerve?

CN 9

30

Carotid Sinus Massage does what to the baroreceptor firing and what is the result?

Increases firing (hering nerve) and parasymp. influence prolongs AV refractory period

31

Woman with Osteoporosis and HTN? Why?

HCTZ; increases Calcium (HyperGLUC)

32

1st generation Antihistamines are?

Diphenhydramine, Dimenhydrinate, chlorpheniramine and promethazine
Amine, nate, azine

33

2nd generation Antihistamines are

Loratadine, fexofenadine, desloratadine and cetirizine
-adine or izine

34

VZV histology?

Bx: Multinucleated inclusion-bearing giant cells

35

Anabolic steriods (methyltestosterone) can lead to?

Acne

36

What differentiates between Direct and Indirect Inguinal Hernia?

Inferior epigastric vessels

37

Prostacyclins do what?

inhibit platelet aggregation

38

HBV helps HDV (delta agent) in what way?

Delta agent is coated with HBsAg to get into cells

39

With Chronic Lung Rejection, where do the immune rxn affect?

small airways

40

What cytokine moves Smooth Muscle Cells from the Media to Intima? Who secretes it? What does it do?

PDGF and platelets;
migrates SMC from media to intima and proliferate in the intima

41

Platelets secrete TGF-B. What does it do?

Smooth muscle cell chemotaxis and interstitial collagen production

42

Lissencephaly results in? What do you see in MRI?

Results in: congenital absence of gyri
MRI: smooth brain

43

Pseudotumor Cerebri what is the problem? What does it lead to?

Increased ICP with normal CSF and normal neuroimaging, optic nerve atrophy and blindness

44

Spherules packed in spores

Coccidiodides immitis

45

DM neuropathy is associated with?

Endoneural arteriole hyalinization

46

Small Erythematous papules on the palms with excoriations, scattered vesicles and pustules on the finger webs, palms and wrist creases

Scabies mite and eggs

47

Coffee Ground Color Indicates?

That the bleeding has touched acid=>oxidation of heme

48

Increases in Preload do what to sarcomere length?

Increase

49

Cleft Lip and palate, polydactyly, rockerbottom feet, holoprosencephaly

Trisomy 13

50

Trisomy 13 Cause?

Meiosis I Non disjunction

51

Coughing or Sneezing=>urine coming out; what kind of dysfunction is it?

Stress Urinary Incontinence=>Urethral Sphincter dysfunction

52

Sudden Overwhelming Need to empty bladder; What kind of dysfunction is it?

Urge Incontinence=>Detrussor overactivity

53

Constant involuntary dripping; What kind of dysfunction is it?

Overflow incontinence=>impair detrussor contractility