Week 1 Bacterial Skin Infections - Diebel Flashcards Preview

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Flashcards in Week 1 Bacterial Skin Infections - Diebel Deck (13):
1

Acne/Folliculitis

infection of hair follicles by propionibacterium acnes
bacteria realease lipases to digest trapped oil, bacterial metabolism activates local inflammation

2

Impetigo

-most common in children
-skin flakes or peels off
-highly contagious
-can be caused by Staph or Strep

3

Staph Aureus

-most common infectous agent of surgical wounds
-Protein A (binds Fc portion of IgG)
-Coagulase (cloaking mechanism)
-Hemolysins and leukocidins (destroys RBCs WBCs)

FOR DEEP TISSUE INVASION-
Hyaluronidase
Staphylokinase
LIpase

TOXINS
TSST-1 (superantigen that promotes excessive release of IL-1 and TNF)

Scalded Skin syndrome- ET-A and ET-B (epidermis seperates skin and sloughs off)

4

Strep Pyogenes

Streptokinase
M protein
Hyalurondiase
DNase
Streptolysin O (destroys RBCs)
Streptolysin S (destroys WBC)

TOXINS
TSS through exotoxin A (superantigen)
Necortizing fascitis through exotoxin B

5

Gram (-)

pseudomonas Arginosa causing hot tub folliculitis

6

Gram (+) Rod

Clostiridum Perfringens causes gas gangreen

7

Gram (+) Cocci

Strep and Staph

8

Catalase test

differentiate between strep(-) and staph (+)

9

Coagualse Test

differentiate between Staph auerus (+) and (straph saprofiticus and straph epidermis)

10

What causes is Cellulitis

Staph or Strep or clostridium

11

Clostridium Perfringens

non-motile
forms collections of gas under the skin that crackle when touched (crepitus)
bacteria grow in ANAEROBIC

To cure gas gangrene --> surgically remove, or hyperbaric oxygen, antibiotics not effective

12

Rocky Mountain Spotted Fever

Starts in extremities (hands and feet)
spotted rash
obligate intracellular parasite, needs host ATP!)
get from ticks
treat with doxycyclin

13

Lyme Disease

bulls eye rash
from ticks