Flashcards in Week 4 Soft-tissue tumors- Nelson Deck (20):
Describe in one or two sentences the classification scheme for mesenchymal/ soft tissue tumors.
Soft-tissue tumors are classified by the types of tissue that they recapitulate or differentiate to, they be divided into benign and malignant (sarcoma) forms.
Describe the typical pattern of spread of sarcomas when they metastasize
a. Benign soft-tissue tumors outnumber malignant soft-tissue tumors
b. Sarcomas are rare but deadly
c. Usually metastasize via hematogenous routes (to lung and bone)
State the type of cell that gives rise to soft tissue tumors
Most common type of genetic abnormalitiy in soft tissue tumors?
Specific chromosomal abnormalities, usually translocations!
Which imaging technique is most helpful in assessment of soft tissue tumors or extrememties?
benign fatty tumor
malignant fatty tumor
benign lesion following local trauma/ injury
benign fibroblastic proliferation involving fascia or aponeruoses
benign fibroblastic proliferation, but can reoccur
malignant, sarcomatous tumors of fibroblasts
benign tumor showing skeletal muscle differentiation
malignant tumor showing skeletal muscle differentiation
benign tumor showing smooth muscle differentiation
malignant tumor showing smooth muscle differentiation
benign lesion of blood vessel
benign lesion of lympathics
malignant. Showing endothelial differentiation
malignant vascular tumors