Flashcards in Week 3 Case Study- Johns Deck (9)
What do ET-A and ET-B target?
protein desmoglein- breaks apart a key protein to protein interacton that serves to hold together desmosome cells
What does ET-A cause? What is it encoded by?
Encoded by lysogenized phage
What does ET-B cause? What is it encoded by?
Encoded by a plasmid
SSSS vs. TEN?
TEN- separation of epidermis from dermis, older patients, sulfa drugs
SSSS- stratum granulosum from keratinocytes, young children, recent staph infections
Differentiate between SSSS and pemphigus
Pemphigus punch biopsy reveal antibody to desmoglein
Clinical presentations of a bad sore throat and rash? S. pyogenes vs. EBV?
S. pyogenes - causative agent of scarlet fever, ages 5-15
EBV- causes mono. Before 5 or young adults/teenagers
Group A Strep
High fever, rash, red eyes, enlarged lymph nodes
No lab that helps