Week 3 Case Study- Johns Flashcards Preview

Skin/ Musculoskeletal > Week 3 Case Study- Johns > Flashcards

Flashcards in Week 3 Case Study- Johns Deck (9)
Loading flashcards...
1

What do ET-A and ET-B target?

protein desmoglein- breaks apart a key protein to protein interacton that serves to hold together desmosome cells

2

What does ET-A cause? What is it encoded by?

Bullous Impetigo
Encoded by lysogenized phage

3

What does ET-B cause? What is it encoded by?

SSSS
Encoded by a plasmid

4

SSSS vs. TEN?

TEN- separation of epidermis from dermis, older patients, sulfa drugs
SSSS- stratum granulosum from keratinocytes, young children, recent staph infections

5

Differentiate between SSSS and pemphigus

Pemphigus punch biopsy reveal antibody to desmoglein

6

Clinical presentations of a bad sore throat and rash? S. pyogenes vs. EBV?

S. pyogenes - causative agent of scarlet fever, ages 5-15

EBV- causes mono. Before 5 or young adults/teenagers

7

Scarlet Fever

Group A Strep
Trunk rash
Red Tongue

8

Kawasaki Disease

Autoimmune vasculitis
High fever, rash, red eyes, enlarged lymph nodes

No lab that helps

9

SSSS
Treatment?

coagulase positive staph
ETB toxin
exfoliaton of skin
conjunctive reddness
fever
face and around mouth
Penicillinase-resistant penicillin