Week 4 NeuroCommunication- Fitz Flashcards Preview

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Flashcards in Week 4 NeuroCommunication- Fitz Deck (3)
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Botulinum Toxin

destroy components of the docking apparatus that are required for vesicle fusion in neurons that utilize acetylchoine as a neurotransmitter: PREVENTING MUSCLE CONTRACTION


Tricyclin antidepressants, cocain, amphetamine, SSRIs

block re-uptake


Tetanus toxin

-destroys the components of the docking apparatus, selectively in inhibitory neurons.
-Toxin is transported retrogradely back across synapse
-Taken up by synaptic terminals where it blocks release of INHIBITORY neurotransmitters
-Motor neurons become OVERACTIVE
-Spastic paralysis