Why Subtle Gene Changes Mean Every Child is Different - Symposia Part 2 Flashcards

1
Q

ICS =

A

Inhaled Corticosteroid

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2
Q

LABA =

A

Long-acting beta 2 agonist

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3
Q

LTRA =

A

Leukotriene receptor antagonist

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4
Q

Asthma - Suspected v Diagnosed

A
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5
Q

LABA, ICS, LTRA Comparisons

A
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6
Q

Case Study - Asthma - Jamie, 7yo

  • Recurrent Wheeze, 2 hospital admissions and 2 further A&E visits over 12 months, managed with inhaled salbutamol plus intravenous prednisolone
  • Low lung function with 15% response to bronchodilator
  • On Seretide 125 inhaler plus aerochamber 1 puff twice daily plus regular oral motelukast
  • Still uses the blue inhaler several times daily
  • Proper inhaler technique, he is taking it well
  • Very organised family, you don’t think there is a problem with not taking medicines regularly
A
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7
Q

Case Study - Asthma - Jamie, 6 YO

  • Active and well until 6 months ago
  • now coughs a lot when chasing football, falls behind his friends during play, coughs at night
    *
A
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8
Q

Case Study - Asthma, Ben 10YO

  • Hay fever symptoms, exposed to cigarette smoke, wheezes when he plays with cats
  • Asthma control is poor
  • On inhaled beclomethasone 200 micrograms 2x daily
  • How would we manage this child?
A
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9
Q

… Exposure reduces trigger load and can reduce hospital admissions (Asthma)

A

HDM

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10
Q

Summary - Individualising asthma management

A
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11
Q

Triggers have a cumulative effect - leading to underlying … (Asthma/allergies)

A

inflammation

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