Anaesthetic Drugs Flashcards Preview

Pharmacology > Anaesthetic Drugs > Flashcards

Flashcards in Anaesthetic Drugs Deck (19)
Loading flashcards...
1
Q

Examples of Fluranes

A

Isoflurane, Halothane

2
Q

Mechanism of action of Fluranes

A

Bind allosterically to GABA receptors, increasing sensitivity, increasing Cl conductance hyperpolarising the membrane

3
Q

ADRs of Fluranes

A

Resp depression, Cognitive dysfunction

4
Q

Mechanism of action of Nitrous oxide

A

Inhibit NMDA receptors reducing Ca influx

5
Q

Mechanism of action of Propofol

A

Bind allosterically to GABA receptors increasing sensitivity, increasing Cl influx hyperpolarising the membrane

6
Q

ADRs of Propofol

A

Resp depression, Hypotension

7
Q

Define MAC

A

Conc in lungs at which 50% of population won’t respond to surgical stimuli

8
Q

Factors increasing MAC

A

Youth, High temp, Pregnancy, Alcoholism, Stimulants

9
Q

Factors decreasing MAC

A

Opioids, Anaesthetics, Low temp

10
Q

Guedal signs stage 1

A

Analgised but conscious

11
Q

Guedal signs stage 2

A

Hypertonic, Increased eye movements

12
Q

Guedal signs stage 3

A

Muscles relaxed, Reduced resp rate

13
Q

Guedal signs stage 4

A

Resp depression

14
Q

Phases of anaesthesia

A

Reveiw, Peri-surgical monitoring, Induction, Maintenance, Recovery

15
Q

Actions in the review phase of anaesthesia

A

Review patient history, Assess airways

16
Q

Actions in the peri-surgical monitoring phase of anaesthesia

A

Measure physiological parameters

17
Q

Actions in the induction phase of anaesthesia

A

Give IV agent, inhaled agents started

18
Q

Actions in the maintenance phase of anaesthesia

A

Maintain unconsciousness

19
Q

Actions in the recovery phase of anaesthesia

A

Inhaled agents stopped, antidotes given