Anaesthetic Drugs Flashcards Preview

Pharmacology > Anaesthetic Drugs > Flashcards

Flashcards in Anaesthetic Drugs Deck (19):
1

Examples of Fluranes

Isoflurane, Halothane

2

Mechanism of action of Fluranes

Bind allosterically to GABA receptors, increasing sensitivity, increasing Cl conductance hyperpolarising the membrane

3

ADRs of Fluranes

Resp depression, Cognitive dysfunction

4

Mechanism of action of Nitrous oxide

Inhibit NMDA receptors reducing Ca influx

5

Mechanism of action of Propofol

Bind allosterically to GABA receptors increasing sensitivity, increasing Cl influx hyperpolarising the membrane

6

ADRs of Propofol

Resp depression, Hypotension

7

Define MAC

Conc in lungs at which 50% of population won't respond to surgical stimuli

8

Factors increasing MAC

Youth, High temp, Pregnancy, Alcoholism, Stimulants

9

Factors decreasing MAC

Opioids, Anaesthetics, Low temp

10

Guedal signs stage 1

Analgised but conscious

11

Guedal signs stage 2

Hypertonic, Increased eye movements

12

Guedal signs stage 3

Muscles relaxed, Reduced resp rate

13

Guedal signs stage 4

Resp depression

14

Phases of anaesthesia

Reveiw, Peri-surgical monitoring, Induction, Maintenance, Recovery

15

Actions in the review phase of anaesthesia

Review patient history, Assess airways

16

Actions in the peri-surgical monitoring phase of anaesthesia

Measure physiological parameters

17

Actions in the induction phase of anaesthesia

Give IV agent, inhaled agents started

18

Actions in the maintenance phase of anaesthesia

Maintain unconsciousness

19

Actions in the recovery phase of anaesthesia

Inhaled agents stopped, antidotes given