Anti-arrhythmic Drugs Flashcards Preview

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Flashcards in Anti-arrhythmic Drugs Deck (20):
1

Examples of Class I anti-arrhythmic Drugs

Lidocaine, Flecainide

2

Mechanism of action of Class I anti-arrhythmic Drugs

Block Na channels, Slow conductance in phase 0 of cardiac action potential

3

ADRs of Class I anti-arrhythmic Drugs

Hypotension, Long QT, Dizziness, Confusion, Insomnia, Seizures, GI upset

4

Indications for Class I anti-arrhythmic Drug use

Rhythm control -AF

5

Examples of Class II anti-arrhythmic Drugs

Atenolol, Bisoprolol

6

Mechanism of action of Class II anti-arrhythmic Drugs

Beta blockers, Reduce SNS input slowing conduction through the AV node

7

ADRs of Class II anti-arrhythmic Drugs

Bronchospasm, Hypotension, Reduced contractility

8

Indication for Class II anti-arrhythmic Drug use

Rate control -SVT, Sinus tachycardia

9

Examples of Class III anti-arrhythmic Drugs

Amiodarone, Sotalol

10

Mechanism of action of Class III anti-arrhythmic Drugs

Block K channels preventing repolarisation increasing the refractory period

11

ADRs of Amiodarone

Arrhythmia, Pulmonary fibrosis, Photosensitivity, Thyroid disease, Liver damage

12

ADRs of Sotalol

Arrhythmia, Fatigue, Insomnia

13

Indications for Class III anti-arrhythmic Drug use

Rhythm control - most arrhythmias

14

Example of Class IV anti-arrhythmic Drugs

Verapamil

15

Mechanism of action of Class IV anti-arrhythmic Drugs

Block Ca channels, reducing influx of Ca in the cardiac and pacemaker potentials, slowing conductance through the AV node

16

ADRs of Verapamil

Hypotension, GI upset

17

Indications for Class IV anti-arrhythmic Drug use

Rate control - SVT

18

Mechanism of action of Adenosine

Activate alpha 1 receptors opening K channels, causes hyperpolarisation increasing the refractory period, slows conductance through the AV node

19

ADRs of Adenosine

Nausea, Lightheadedness, Sense of impending doom

20

Indications for Adenosine use

Acute management of SVT