Flashcards in Diuretics Deck (16):
1
Examples of loop diuretics
Furosemide, Bumetanide
2
Mechanism of action of loop diuretics
Inhibit Na/K/2Cl co-transporter in the TAL
3
ADRs of loop diuretics
Hypokalaemia, Hypovolaemia, Anaphylaxis, Myalgia (Bumetanide), Ototoxicity (Furosemide)
4
DDIs of loop diuretics
Hypokalaemia with steroids
5
Examples of thiazide diuretics
Bumetanide
6
Mechanism of action of thiazide diuretics
Inhibit Na/Cl co-transporter in the DCT
7
ADRs of thiazide diuretics
Gout, Hypokalaemia, Erectile dysfunction, Hypovolaemia
8
DDIs of thiazide diuretics
Hypokalaemia with steroids
9
Example of K sparing diuretic
Amiloride
10
Mechanism of action of K sparing diuretics
Inhibit ENaC in the DCT and CT
11
ADRs of K sparing diuretics
Hyperkalaemia, Hypovolaemia
12
DDIs of K sparing diuretics
Hyperkalaemia with ACE-I
13
Example of aldosterone antagonist
Spirononlactone
14
Mechanism of aldosterone antagonists
Reduce the number of ENaC
15
ADRs of aldosterone antagonists
Hyperkalaemia, Hypovolaemia, Painful gynaecomastia
16