Diuretics Flashcards Preview

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Flashcards in Diuretics Deck (16):
1

Examples of loop diuretics

Furosemide, Bumetanide

2

Mechanism of action of loop diuretics

Inhibit Na/K/2Cl co-transporter in the TAL

3

ADRs of loop diuretics

Hypokalaemia, Hypovolaemia, Anaphylaxis, Myalgia (Bumetanide), Ototoxicity (Furosemide)

4

DDIs of loop diuretics

Hypokalaemia with steroids

5

Examples of thiazide diuretics

Bumetanide

6

Mechanism of action of thiazide diuretics

Inhibit Na/Cl co-transporter in the DCT

7

ADRs of thiazide diuretics

Gout, Hypokalaemia, Erectile dysfunction, Hypovolaemia

8

DDIs of thiazide diuretics

Hypokalaemia with steroids

9

Example of K sparing diuretic

Amiloride

10

Mechanism of action of K sparing diuretics

Inhibit ENaC in the DCT and CT

11

ADRs of K sparing diuretics

Hyperkalaemia, Hypovolaemia

12

DDIs of K sparing diuretics

Hyperkalaemia with ACE-I

13

Example of aldosterone antagonist

Spirononlactone

14

Mechanism of aldosterone antagonists

Reduce the number of ENaC

15

ADRs of aldosterone antagonists

Hyperkalaemia, Hypovolaemia, Painful gynaecomastia

16

DDIs of aldosterone antagonists

Hyperkalaemia with ACE-I