Antibiotic Drugs Flashcards Preview

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Flashcards in Antibiotic Drugs Deck (16):
1

Targets of mechanisms of action of antibiotics

DNA synthesis, Protein synthesis, Cell wall synthesis

2

Antibiotics that target DNA synthesis

Quinolones, Folic acid inhibitors

3

Antibiotics that target protein synthesis

Aminoglycosides, Macrolides, Tetracyclines

4

Antibiotics that target cell wall synthesis

Beta-lactams, Glycopeptides

5

Antibiotics that are concentration dependant

Quinolones, Aminoglycosides

6

Antibiotics that are time dependant

Macrolides, Beta-lactams, Glycopeptides

7

ADRs of Quinolones

Nausea, Vomiting, Headache, Insomnia, C. Diff, Long QT

8

ADRs of Folic acid inhibitors

Hyperkalaemia

9

ADRs of Aminoglycosides

Nephrotoxicity, Ototoxicity

10

ADRs of Macrolides

Nausea, Vomiting

11

ADRs of Tetracyclines

Nausea, Vomiting, Teeth staining, Tinnitis, Reduced foetal bone growth

12

ADRs of Penicillins

Allergy, Diarrhoea, Nausea, Neurotoxicity, Hives, Erythema, Colitis, Angioedema

13

ADRs of Cephalosporins

C. Diff, Vomiting, Headaches, Allergy

14

ADRs of Glycopeptides

Nephrotoxicity, Ototoxicity, Bone marrow damage

15

Mechanisms of antibiotic resistance

Inactivate antibiotics, Alter target site, Alter physiological pathways, Expel drug from cell, Reduce influx into cell

16

Mechanisms of antibiotic resistance spread

Horizontal transfer by conjugation