Antibiotic Drugs Flashcards Preview

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Flashcards in Antibiotic Drugs Deck (16)
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1
Q

Targets of mechanisms of action of antibiotics

A

DNA synthesis, Protein synthesis, Cell wall synthesis

2
Q

Antibiotics that target DNA synthesis

A

Quinolones, Folic acid inhibitors

3
Q

Antibiotics that target protein synthesis

A

Aminoglycosides, Macrolides, Tetracyclines

4
Q

Antibiotics that target cell wall synthesis

A

Beta-lactams, Glycopeptides

5
Q

Antibiotics that are concentration dependant

A

Quinolones, Aminoglycosides

6
Q

Antibiotics that are time dependant

A

Macrolides, Beta-lactams, Glycopeptides

7
Q

ADRs of Quinolones

A

Nausea, Vomiting, Headache, Insomnia, C. Diff, Long QT

8
Q

ADRs of Folic acid inhibitors

A

Hyperkalaemia

9
Q

ADRs of Aminoglycosides

A

Nephrotoxicity, Ototoxicity

10
Q

ADRs of Macrolides

A

Nausea, Vomiting

11
Q

ADRs of Tetracyclines

A

Nausea, Vomiting, Teeth staining, Tinnitis, Reduced foetal bone growth

12
Q

ADRs of Penicillins

A

Allergy, Diarrhoea, Nausea, Neurotoxicity, Hives, Erythema, Colitis, Angioedema

13
Q

ADRs of Cephalosporins

A

C. Diff, Vomiting, Headaches, Allergy

14
Q

ADRs of Glycopeptides

A

Nephrotoxicity, Ototoxicity, Bone marrow damage

15
Q

Mechanisms of antibiotic resistance

A

Inactivate antibiotics, Alter target site, Alter physiological pathways, Expel drug from cell, Reduce influx into cell

16
Q

Mechanisms of antibiotic resistance spread

A

Horizontal transfer by conjugation