Asthma Drugs Flashcards Preview

Pharmacology > Asthma Drugs > Flashcards

Flashcards in Asthma Drugs Deck (16):
1

Examples of Beta agonists

Salbutamol, Salmeterol

2

Mechanism of action of beta agonists

Activate Beta receptors, increasing intracellular Ca, causing bronchodilation

3

ADRs of beta agonists

Tachycardia, Dysrhythmia, Palpitations, Tremor

4

Half-life of salbutamol

4hrs

5

Half-life of salmeterol

12hrs

6

DDIs of beta agonists

Not effective if given with beta bockers

7

Mechanism of action of inhaled corticosteroids

Down regulate interleukin 1 and 6

8

ADRs of inhaled corticosteroids

Sore throat, Oral thrush

9

Examples of methylaxines

Theophyline, Aminophylline

10

Mechanism of action of methylaxines

Antagonise adenosine receptors

11

ADRs of methylaxines

Nausea, Vomiting, Reflux, Arrhythmia, Seizures

12

DDIs of methylaxines

Effected by inducers and inhibitors

13

Examples of anticholinergics (asthma)

Ipratropium bromide, Tiotropium bromide

14

Mechanism of action of anticholinergics (asthma)

Antagonise ACh receptors reducing bronchoconstriction and mucus secretion

15

ADRs of anticholinergics

Dry mouth, Urine retention, Glaucoma

16

Management pathway for asthma

1. SABA
2. Add inhaled steroid
3. Add LABA
4. Increase steroids
5. Add anticholinergic, Methylaxine, or leukotriene receptor blocker
6 Add oral steroids