Anti-emetic Drugs Flashcards Preview

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Flashcards in Anti-emetic Drugs Deck (14):
1

Example of dopamine antagonists (Anti-emetics)

Domperidone

2

Mechanism of action of dopamine antagonists (Anti-emetics)

Reduce signalling from the posterema to medullary centre

3

ADRs of dopamine antagonists (Anti-emetics)

Hyperprolactinaemia

4

Example of 5HT antagonists (Anti-emetics)

Ondansteron

5

Mechanism of action of 5HT antagonists (Anti-emetics)

Reduce signalling from medullary centre to the stomach

6

ADRs of 5HT antagonists (Anti-emetics)

Headaches, Constipation, Flushing

7

Example of anti-muscarinics (Anti-emetics)

Hyoscine

8

Mechanism of action of anti-muscarinics (Anti-emetics)

Reduce signalling to and from the medullary centres

9

ADRs of anti-muscarinics (Anti-emetics)

Bradycardia, Dry mouth, Blurred vision, Constipation, Difficulty urinating

10

Mechanism of action of Metaclopramide

Antagonise dopamine, 5HT, and ACh

11

ADRs of Metaclopramide

Extrapyramidal signs, Glactorrhoea

12

Example of histamine antagonists (Anti-emetics)

Cyclizine

13

Mechanism of action of histamine antagonists (Anti-emetics)

Reduce signalling from medullary centre to the stomach

14

ADRs of histamine antagonists (Anti-emetics)

Long QT