Antiviral Drugs Flashcards Preview

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Flashcards in Antiviral Drugs Deck (7)
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1
Q

Examples of M2 channel blockers

A

Amantidine, Rimantidine

2
Q

Mechanism of action of M2 channel blockers

A

Block M2 ion channel, preventing H influx, preventing uncoating

3
Q

ADRs of M2 channel blockers

A

GI upset, Dizziness, Hypotension, Confusion, Insomnia, Hallucinations

4
Q

Examples of neurominidase inhibitors

A

Zanamivir, Oseltamivir

5
Q

Mechanism of action of neurominidase inhibitors

A

Competitively bind to neurominidase, prevents new virons from budding off

6
Q

ADRs of neurominidase inhibitors

A

GI upset, Headaches, Nose bleeds, Resp depression, Bronchospasm

7
Q

When should treatment with neurominidase inhibitors should be started

A

Within 48hrs of symptoms