Digestion, Absorption, & Vomit Flashcards

1
Q

Amino Acid are bound by ____ linkage

A

peptide

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2
Q

Where does hydrolysis occur?

A

Digestion

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3
Q

Which rxn results in amino acids binding to each other?

A

Condensation

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4
Q

What enzyme digests proteins?

A

Pepsin

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5
Q

Where does pepsin occur at?

A

Stomach

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6
Q

Besides dietary protein, what else does pepsin digest?

A

Collagen (intercellular connective tissue in meats)

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7
Q

Where does the protease enzyme get secreted from and into?

A

From pancreas to small intestines

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8
Q

_____ and _____ split whole and partially digested proteins into peptides only

A

Trypsin + Chymotrypsin

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9
Q

Trypsin + Chymotrypsin split whole and partially digested _____ into _____ only

A

proteins into peptides

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10
Q

What splits peptides into individual amino acid?

A

Carboxypolypeptidase

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11
Q

What does carboxypolypeptidase do?

A

Splits peptides into individual amino acids

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12
Q

Most abundant fats in the diet are ________

A

triglycerides

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13
Q

Where is lingual lipase secreted?

A
  1. Tongue
  2. Stomach
  3. Pancrease
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14
Q

Bile salts form mixed micelles with the products of lipid digestion and enhancing the absorption of lipids by the _____ cells in the ileum

A

epithelial (enterocytes)

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15
Q

Bile salts form mixed micelles with the products of lipid digestion and enhancing the absorption of lipids by the epithelial (enterocytes) cells in the ________

A

ileum

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16
Q

What parts of the digestion does limited digestion of triglycerides occur?

A
  1. Tongue

2. Stomach

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17
Q

In the enterocytes, free FA are re-converted to triglycerides and packaged as _____ and absorbed by the _______

A

chylomicrons + lymphatics

18
Q

What are the transporters involved in glucose absorption?

A

Na+ coupled SGLT-1

19
Q

What are the transporters involved in galactose absorption?

A

Na+ coupled SGLT-1

20
Q

What are the transporters involved in fructose absorption?

A

Faciliated diffusion via GLUT5 transporter

21
Q

Carbohydrates are absorbed as onosaccharides at the _______ in the small intestines

A

brush border

22
Q

To absorb Vit. B12, they must bind to _________

A

intrinsic factor

23
Q

What are the fat-soluble vitamins?

24
Q

How are the fat-soluble vitamins absorbed?

A

Requires bile micells for absorption and enter enterocytes by simple diffusion

25
How are water-soluble vitamins absorbed?
Carriers that are Na+ co-transporters
26
Where specifically does water get absorbed?
Large intestines
27
Absorption of water involves the ______ gradient
osmotic
28
What is the oral hydration therapy?
Restores body fluid volume by ingesting fluid w/ Na+ and glucose and that uptake drives fluid absorption
29
What channel absorbs calcium?
TRPV6 in all segments
30
Which gets absorbed in greater amounts, monovalent or bivalent ions?
Monovalent; bivalent ions only 1/50 as great as normal absorption of monovalent
31
Where are ions absorbed?
Intestinal mucosa
32
Where is iron absorbed?
Small intestine
33
Where does the brown color of feces come from?
Derivative of bilirubin
34
What part of the brain is the emetic center?
Medulla
35
Chemo-receptor trigger zone is also known as....
Area postrema
36
Which of the following would be most associated with the feeling of wanting to vomit as a result of irritation from blood-borne emetics? ``` A. Inner Ear B. Area postrema C. Medulla D. Answers A, B and C E. Answers B and C ```
E. Answers B and C
37
Select the correct answer. The Area postrema ``` A. Contains serotonergic neurons B. Lacks the blood-brain-barrier C. Is a circumventricular organ D. Has fenestrated capillaries E. Answers A-D are correct ```
E. Answers A-D are correct
38
Which of the following would be most associated with the feeling of wanting to vomit as a result of irritation from local irritants? ``` A. Stomach B. Small intestines C. Serotonin binding to serotonin receptors D. Answers A, B and C E. Answers B and C ```
D. Answers A, B and C
39
Which of the following would be most associated with the feeling of motion sickness? ``` A. Inner Ear B. Cerebellum C. Medulla D. Answers A and C E. Answers A, B and C ```
E. Answers A, B and C
40
Which of the following emetics utilizes the LAT transporter? A) Cytotoxic drugs B) Opioids C) Cholinomimetics D) L-DOPA
D) L-DOPA
41
Chose the factors or structures that may regulate/influence the emetic response. l) Hippocampus, ll) Amygdala, lll) Somatosensory cortex ``` A) l B) ll C) lll D) l, ll & lll E) ll & lll ```
D) l, ll & lll