Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Microbiology > DNA Viruses Part 2 > Flashcards

DNA Viruses Part 2 Flashcards

1
Q

Smallest virus

A

Parvoviridae - Parvovirus (20nm)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Parvoviridae Features

A

Smallest virus
ssDNA
Icosahedral Symmetry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Spread of Parvoviridae

A

Respiratory route
Blood Transfusion
Transplacental transmission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Parvoviridae attacks which antigen

A

Attack P antigen of RBC precursor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Genotypes and Serotypes of Parvoviridae

A

3 genotypes - Parvoviridae 1(M/C), 2 and 3
Serotype 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Conditions associated with Parvovirus B19

A

Erythema infectiosum (5th disease,slapped chick appearance)
Gloves and socks Syndrome
Arthritis, Arthralgia
Aplastic crisis (in Hemolytic anemia)
Pure red cell aplasia (PRCA)
Hydrops fetalis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Erythema infectiosum Clinical features

A

AKA 5th disease/Slapped cheek appearance
Macular erythematous rash on cheek
Lacy rash on rest of body
Self limiting condition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Gloves and socks Syndrome also known as

A

PPGSS - Papular Perpeuric Gloves and Socks Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pure red cell aplasia (PRCA) is associated with which conditions

A

Parvo B19 virus
Thymoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Diagnosis of Parvoviridae

A

ELISA For Antibody
PCR for DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

First disease AKA

A

Measles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Second disease AKA

A

Scarlet fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Third disease AKA

A

German measles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Fourth disease AKA

A

DUKE (Obsolete)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fifth disease AKA

A

Slapped cheek/Erythema infectiosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Sixth disease AKA

A

Roseola infantum/HHV 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Papovaviridae Family includes

A

Papilloma virus
Polyoma Virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Polyoma Virus includes

A

Merkel cell virus (MCV)
SV40 (Simian Vacuolatin
JC Virus
BK Virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Merkel cell virus known to cause

A

Merkel cell carcinoma - Neuroendocrine tumor
CK 7 -ve, CK 20 +ve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

SV40 (Simian Vacuolating) is associated with

A

Non pathogenic to human
Associated with Mesothelioma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

JC Virus attacks which cells and causes

A

Attacks oligodendrocytes
Causes demyelinating syndrome - Progressive Multifocal Leukoencephalopathy (PMLE)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Myelin stain used in PMLE and finding

A

Luxol fast blue - Negative in PMLE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

BK Virus causes

A

Interstitial Nephritis
Hemorrhagic Cystitis
Usually seen in Post transplant pt.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Urine M/E finding in BK virus

A

Large cell - Decoy cells (High N/C ratio mimics cancer)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Human Papilloma virus involves which organs
Cutaneous involvement - HPV 1,2,3 (low risk) ; HPV 5,8 (High risk) Mucosal involvement - HPV 6,11(low risk) ; HPV 16,18,31,33,35 (High risk)
26
HPV 1,2,3 causes
Low risk Plantar wart Filiform wart
27
HPV 5,8 known to cause
Epidermodysplasia Verruciforms/Tree man Syndrome - a/w With chr. 17
28
HPV 6,11 Causes
Laryngeal Papillomatosis Condylomata Acuminatum (Genital warts)
29
L1 capsid protein of HPV is used for
Used for preparing vaccine
30
E2 protein of HPV is used as
Controller
31
E4 and E5 Protein of HPV known to show which structure
Koilocytosis - Koilocyte +ve
32
E6 and E7 Protein of HPV is responsible for
Carcinogenesis - Squamous epithelium - Cervical cancer, Penile cancer, Anal canal cancer, Oral cancer, Laryngeal Cancer, esophageal cancer)
33
E6 protein inactivates which gene
P53 (Policeman)
34
E7 protein of HPV inactivates which gene
RB gene (Governer)
35
Diagnosis of HPV Infection
Screening - Pap smear Confirmatory - Biopsy (Koilocyte +) Molecular tests - PCR, Hybrid capture assay
36
Vaccines for HPV
Cervarix Gardasil Gardasil 9
37
Cervarix vaccine adjuvant and provides protection against
Bivalent Adjuvant - ASO4 (Act on TLR's - enhances immunity) Protection - HPV 16,18
38
Gardasil vaccine provides protection against
Quadrivalent Protection against HPV 6,11,16,18
39
Poxviridae family includes
Vaccinia (Cowpox) Variola (Smallpox) Molluscum Contagiosum Monkey pox
40
Size, shape, symmetry, and replication site in Poxviridae family
Size - 300nm (Largest) Shape - Box/brick With Dumbell DNA core Symmetry - Complex Replication site - Cytoplasm
41
Variola/small pox incubation period
12 days
42
Crop and fever in case of Smallpox
No crop No fever with crop - fever subsides with rash
43
Distribution of rash in Smallpox
Centrifugal (from extremities) to centripetal (Trunk)
44
Vaccine used against Variola/Smallpox
1st vaccine - Edward Jenner(Using cowpox) Live vaccinia vaccine - freeze dried preparation
45
Cytopathic effect shown by Variola and Vaccinia
Vaccinia - Guarnieri body Variola - Paschen body
46
Vaccinia on Chorioallantoic Membrane shows
Large, hemorrhagic necrotic lesions
47
Variola on Chorioallantoic Membrane shows
Small, non hemorrhagic lesions
48
Molluscum Contagiosum is most commonly caused by
Molluscum contagious virus 1 (M/C) and 2
49
Transmission of Molluscum contagious virus
In child and adults - by contact
50
Characteristic Findings of Molluscum Contagiosum lesions
Tam color umbilicated lesions - on pressing, curdy discharge Seen all over body except Palms, soles
51
Cytopathic effect caused by Molluscum Contagiosum virus
Cup shaped Henderson Patterson bodies (HP Body)
52
Stained used to see Henderson Patterson bodies
Phloxine Tartarate stain - also used to stain Paneth cells (GIT)
53
E/M finding in case of Molluscum contagious virus
Brick/box shape with Dumbell core
54
Reservoir of Monkeypox
Rodents
55
Mode of transmission of Monkey pox
Zoonotic - bites, scratches, Consumption of bush meat Human to human transmission possible
56
Incubation period and clinical features of Monkey pox
IP - 2 weeks C/F - Fever,Rash, Lymphadenopathy
57
Shape of Adenovirus
Space vehicle shape
58
Fibers rising from surface of Adenovirus helps in
Attachment
59
Clinical features caused by Adenovirus
Hemorrhagic Cystitis Infant diarrhea Involvement of Eyes Respiratory diseases
60
Which type of Adenovirus involved in case of Hemorrhagic Cystitis
11,21
61
Type of Adenovirus responsible for Infant diarrhea
40,41
62
Clinical features related to eyes caused by Adenovirus
Epidemic Keratoconjunctivitis/Shipyard eye Pharyngoconjunctival fever/swimming pool Conjunctivitis
63
Epidemic Keratoconjunctivitis/Shipyard eye caused by which adenovirus
AKA Epidemic follicular conjunctivitis - Corneal opacities Type 8,19,37
64
Pharyngoconjunctival fever/ swimming pool Conjunctivitis clinical features and types involved
H/O swimming Pharyngitis Follicular conjunctivitis (U/L or B/L) In children's
65
Respiratory diseases caused by Adenovirus and types involved
URTI - 1,2,3,5 Pneumonia - 3,7,21 Transplant recipients - 34,35

Microbiology (37 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions