Endocrine II Flashcards Preview

Board Review - B - Systems Pharmacology > Endocrine II > Flashcards

Flashcards in Endocrine II Deck (25)
1

propylthiouracil

block thyroid peroxidase - inhibit iodine coupling

2

methimazole

block thyroid peroxidase - inhibit iodine coupling

3

tx hyperthyroid pregnant

propylthiouracil

4

adverse methimazole

teratogen

5

adverse propylthiouracil

hepatotoxic

6

levothyroxine

T4

7

triiodothyronine

T3

8

adverse T4 and T3

tachy
heat intolerance
tremor
arrhythmia

9

conivaptan

ADH antagonist

10

tolvaptan

ADH antagonist

11

tx central DI

desmopressin acetate

12

tx turner syndrome

GH

13

oxytocin

stimulate labor, uterine contraction, milk letdown

14

octreotide

somatostatin

15

demeclocycline

ADH antagonist

16

beclomethasone

glucocorticoid

17

dexamethasone

glucocorticoid

18

fludrocortisone

glucocorticoid

19

hydrocortisone

glucocorticoid

20

methylprednisolone

glucocorticoid

21

triamcinolone

glucocorticoid

22

mechanism glucocorticoid

metabolic
catabolic
anti-inflammatory
immunosuppressive

inhibit - NF-kB and phospholipase A2

23

adverse glucocorticoid

iatrogenic cushings

peptic ulcer
steroid diabetes
steroid psychosis

24

adverse stop glucocorticoid

adrenal insufficiency

25

cinacalcet

sensitize Ca-sensing receptor in PTH
-decreased levels of PTH

tx of hyperCa due to primary or secondary hyperPTH