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Flashcards in fungal infections and treatment Deck (15)
1

what does Cryptococcus neoformans cause

meningitis, pneumonia, fungaemia

a type of yeast

2

what does pityriasis versicolor causes

chronic skin infections

a type of yeast

3

what does histoplasma capsulatum cause

pulmonary or disseminated infections

a type of yeast

4

what does aspergillus cause

pulmonary, ocular infections, bronchopulmonary aspergillosis, fungaemia

a type of filamentous fungi

5

what do dematophytes cause

skin, nail infections

a type of filamentous fungi

6

what are the main types of antifungal drugs

triazoles, imidiazole, thiazole
flucytosine
polyenes
terbinafine
griseofulvin
echinocandins
allyamines

7

what does triazole do

blocks p450 and sterol 14 alpha demethylase in the cell wall

8

what does flucytosine do

inhibits protein synthesis

9

what do polyenes do

pore formation in fungal membranes

10

what does terbinafine do

inhibits squalene epoxidase that accumulates toxic sterols in the cell wall

11

what does griseofulvin do

inhibits fungal mitosis

12

what do echinocandins do

inhibit 1,3 beta glucan in the cell wall

13

what are some examples of triazole drugs

fluconazole
itraconazole
posaconazole
voriconazole

14

what are some examples of polyenes

amphotericin and nystatin

15

what are the 4 types of triazoles

fluconazole
itraconazole
posaconazole
voriconazole