Penicillins Flashcards Preview

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Flashcards in Penicillins Deck (15)
1

Methicillin, Oxacillin, Nafcillin, Cloxacillin, Dicloxacillin.

β-Lactamase-resistant Penicillins.

2

Ampicillin & Amoxicillin.

Broad-spectrum penicillins

3

Carbenicillin, Ticaracillin, Azlocillin, Piperacillin.

Extended-spectrum penicillins

4

Broader spectrum than penicillins and cephalosporins, generally beta lactamase resistant

carbapenems

5

Clavulanic acid and salbactam

class A beta lactamase inhibitors

6

Cefalexin, cefuroxime, cefotaxime, cefadroxil

cephalosporins, an alternative to penicillins

7

Vancomycin

Glycoptide, binds to peptide chain
minimal resistance

8

Bacitracin

cyclic peptide
skin and eye infections
bactericidal
cell wall inhibitor

9

sulphonamides and trimethoprim

folate antagonists

10

Tetracycline

30s inhibitor

11

chloramphenicol, erythromycin, clindamycin, streptogramins

50s inhibitor

12

Erythromycin and
clarithromycin

Macrolide
alternative to penicillin

erythromycin- long QT syndrome

13

aminoglycosides

renal toxicity, ototoxicity, neuromuscular block
IV administration

protein synthesis inhibitor

14

tetracyclines

targets 30s
resistant gram negative infection
gut problems, hepatic and renal dysfunction

15

chloramphenicol

broad spectrum
risk of aplastic anaemia

50s