GI Drugs III Flashcards Preview

Pharmacology > GI Drugs III > Flashcards

Flashcards in GI Drugs III Deck (12):
1

anti TNFalpha drug used for IBD

infliximab and adalimumab

2

conditions that infliximab is used for

Crohn's related fistulas and flare ups
rheumatoid arthritis

3

adverse effect of infliximab

reactivation of latent tuberculosis`

4

anti integrins used for IBD and adverse effect

natalizumab

blocks leukocyte integrins and hence can produce multifocal leukoencephalopathy

5

what is irritable bowel syndrome (IBS)

diarrhea or constipation or alternating without structural abnormalities

6

drugs used for IBS

Anticholinergics
5 HT3 antagonist
Opioid agonists
Chloride Channel activators

7

anticholinergics used in IBS

Hyoscyamine
Dicyclomine
Glycopyrrolate
Methscopolamine

8

5-HT3 antagonist used for IBS and adverse effects

Alosetron

constipation, ischemic colitis, infarction

9

opioid agonist used in IBS and mechanism

loperamide --> acts via GI mu opioid receptor --> inhibits ACh release and decrease peristalsis

10

chloride channel activator in IBS

lubiprostone

11

used for pancreatic insufficiency and what it does

pancrelipase
improves digestion of dietary fat, protein, and carbs, and vit ADEK absorption

12

when is pancrelipase used

-chronic pancreatitis, steatorrhea, pancreatectomy, CF insufficiences

-those on weight loss med Orlistat that inhibits gastric and pancreatic lipase (drug decreases absorption of vit ADEK)

Decks in Pharmacology Class (79):