Respiratory Pharmacology II Flashcards Preview

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Flashcards in Respiratory Pharmacology II Deck (16):
1

what causes failure of asthma management

-lack of adherence to medication
-uncontrolled co-morbid conditions
-continued exposure to tobacco smoke, airborne pollutants, allergens, and irritants

2

what are the asthma medications for exacerbations (use mnemonic)

ASTHMA
Albuterol, Pirbuterol, Terbutaline
Steroids
Theophylline
Humidifier O2
Magnesium (severe exacerbation when other methods not working)
Anticholinergics

3

at what point do you add antibiotics as an additional treatment for COPD

when FEV1/FVC ratio is below 49%

4

mnemonic for COPD ts

COPD
Corticosteroids
Oxygen
Prevention (cessation of smoking, infection control, pneumococcal and influenza vaccine)
Dilators (anticholinergics and beta 2 agonists)

5

what are the opioids that are used an antitussives (cough medication)

codeine
dextrometorphan (synthetic codeine)

6

how do opiates work to reduce cough

decrease CNS cough center's sensitivity to peripheral stimuli

7

mechanism of dextrometorphan

suppresses response of cough center but does not have analgesic or addictive potential and is less constipating than codeine

8

name the drug that is a mucolytic agent

NAC
n-acetylcysteine

9

uses of N-acetylcysteine

-management of acetaminophen overdose
-cystic fibrosis to break disulfide bonds in mucus thereby liquefying it and making it easier to cough out

10

H1 antagonist used for respiratory issues

FLaCCiD
Fexofenadine
Loratadine
Cetirizine
Chlorpheniramine
Diphenhydramine

11

drugs used to treat chronic rhinitis

CCAAN

Corticosteroids: beclomethasone and flunisolide
Cromolyn
Alpha adrenergic agonists
Antihistamines
Nasal corticosteroids

12

antihistamines used to treat rhinitis

FLaCCCiD
Fexofenadine
Loratadine
Cetirizine
Chlorpheniramine
Cyproheptadine
Diphenhydramine

13

adverse effects of antihistamines used to tx rhinitis

1st gen - Chlorpheniramine, Cyproheptadine, and Diphenhydramine cross BBB and cause drowsiness

2nd gen - Cetirizine, Fexofenadine, and Loratadine do not produce drowsiness

14

mechanism of alpha adrenergic agonists

constrict dilated arterioles in nasal mucosa and reduce airway resistance

15

examples of alpha adrenergic agonists used in tx of rhinitis

phenylephrine (increase BP and dilate pupil)
pseudoephrine

16

effects of prolonged use of nasal decongestant

rebound nasal congestion after discontinuation of prolonged use

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