Flashcards in Histology - 514-2 Deck (45):
The volume of cells exceeds the volume of extracellular matrix in connective tissues.
The extracellular matrix is much greater.
Name four types of connective tissue
Connective tissue proper
What is an example of embryonic connective tissue?
Name four kinds of CT Proper.
Dense (regular and irregular)
What is an example of specialized CT?
What are two types of supporting CT?
Cartilage (hyaline, elastic, fibrocartilage)
What are all connective tissues derived from?
(embryonic mesenchymal cells)
Which connective tissue cell is most abundant?
Why fibroblasts, not fibrocytes?
Because they are so transformable.
From what cell is a macrophage derived?
(type of WBC - leukocyte)
Trace the cell differentiation that results in an osteoclast
Osteoclast - macrophage - monocyte - hematopoietic stem cell - mesenchyme
Extracellular matrix is found in epithelia
What is ground substance
component of ECM / gel-like amorphous subst
What characterizes Reticular Fibers
Type III collagen
Spongy tissue (bv walls)
What characterizes Elastic Fibers?
made from Elastin
can stretch 150% resting length
What is the most abundant type of collagen?
What type of collagen is a gel-like substance?
What type of collagen is abundant in the placenta?
Which collagen forms anchoring loops in the basal lamina?
What collagen is found in Descement's membrane in the cornea?
What collagen type is found in mineralizing cartilage?
What cell produces collagen?
What are the steps of collagen production?
Preprocollagen - pro collagen - tropocollagen - collagen fibrils
What step is Vitamin C dependent?
Preprocollagen - procollagen
(enzymes depend on C to put into triple helix)
Does tropocollagen have end strands?
No - end strands are removed at this stage
What can bind ECM ground substance to integrin proteins?
What does "areolar" mean?
What are the four kinds of connective tissue proper?
Dense (regular and irregular)
How do Mast Cells "dilute" an area of infection?
Release histamine (vasodilator)
Where are type III collagen fibers found?
Elastic fibers are branched
What's going on with Ehlers-Danlos Syndrome that allows for unusually elastic skin?
Defective Collagen synthesis.
What kind of adipose tissue is multilocular?
What can be considered intracellular CT?
What kind of fat gets its name from an organelle?
Brown - because it is loaded with mitochondria.
Name 3 kinds of cartilage and 2 kinds of bone
Hyaline, Elastic, Fibro-
Compact and Spongy
What membrane surrounds cartilage?
What are chondroblasts surrounded by matrix?
All cartilage contains what type of collagen?
What type of cartilage is the template for endochondral bone formation?
What additional ingredient does elastic cartilage contain?
(found in external ear / epiglottis)
Elastic Cartilage has no perichondrium.
What type of cartilage is found in the TMJ?
Resists compressing and absorbs shock
What type of collagen is found in the TMJ
Type I and II
(Type II only in hyaline/elastic)