Hypersensitivity types (4-5 star!!) Flashcards Preview

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Flashcards in Hypersensitivity types (4-5 star!!) Deck (26):
1

Type I

free antigen binds IgG and causes histamin, bradykinin release= wheal and flare reaction

2

Type II

antibody mediated cytotoxicity--> IgM or IgG bind to fixed antigen on a cell and activate complement--> MAC and cell detruction

3

Type III

Immune complex--> IgG -antigen complex deposit in tissues and ativate complement there, recruiting neutrophils (C5a), incite inflammation

4

Type IV

delayed, T-cell mediated--> sensitized T-cells encounter antigen and activate macrophages= NO Ab involved

5

Acute hemolytic transfusion reaction

type II

6

Acute rheumatic fever

type II

7

Arthus reaction

type II--> is local subacute Ab-mediated HSN, usually due to injection of antigen, forming immune complexes in skin= edema, necrosis, activation of complement (occurs 4-12 hours after an immunization, etc)

8

Asthma

type I

9

contact dermatitis

type IV (nickel, cobalt allergy

10

eczema

type I

11

Graves disease

type II

12

guillan-barre syndrome

type IV

13

graft-vs-host disease

type IV

14

hashimoto thyroiditis

type IV

15

idiopathic thrombocytopenia (ITP)

type II

16

multiple sclerosis (MS)

type IV

17

myasthenia gravis

type II

18

polyarteritis nodosa

type III

19

post-streptococcal glomerulonephritis

type III

20

rheumatoid arthritis

type III

21

rhinitis

type I

22

SLE

type III

23

pernicious anemia

type II

24

erythroblastosis fetalis

type II

25

goodpasture's syndrome

type II

26

PPD skin test

type IV

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