Seizure and Seizure Drugs Flashcards Preview

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Flashcards in Seizure and Seizure Drugs Deck (18):
1

partial seizure

affects one part of brain (gen. temporal)

2

simple seizure

pt. maintains conciousness

3

generalized seizure

spreads to affect more than one part of brain

4

complex seizure

pt loses conciousness

5

staring, quivering of lips or smacking lips

absence (petit-mal) generalized seizure

6

twitching seizure

Myoclonic, generalized

7

muscles get stiff, then starts twitching

Tonic-clonic (grand-mal)

8

gets stiff only

tonic

9

loses muscle tone and just falls to floor

atonic

10

What is status epilepticus (2)

1. complex seizure lasting more than 5 mins OR
2. multiple seizures w/o regaining conciousness in between

11

tx for status epilepticus

IV lorazepam (or diazepam)

12

DOC for absence seizures

ethosuxamide

13

* 7 side effects of phenytoin

1. gingival hyperplasia
2. hirsutism
3. fetal hyantoin syndrome (cleft lip and palate, heart defects, mental retardation)
4. megaloblastic anemia
5. peripheral neuropathies
6. drug-induced lupus
7. Stevens-johnson syndrome

14

5 anti-convulsants that cause stevens-johnson (and 3 other that do too)

1. ethosuxamide
2. lamotrigine
3. carbamazepine
4. phenytoin
5. phenobarbitol
6. Sulfonamides
7. penicillins
8. allopurinol

15

3 drugs used to treat tonic-clonic (grand mal) seizures

1. valproic acid (supposed to be best for generalized)
2. carbamazepine
3. phenytoin

16

best drug for partial seizure

lamotrigine

17

5 drugs that cause agranulocytosis

1. Carbemazepine
2. Clazopine
3. Colchicine
4. Propylthiouracil (PTU)
5. Methimazole

18

6 drugs that induce CYPs ("coronas, guiness, and PBR induce chronic alcoholism")

1. carbamazepine
2. griseofulvin
3. phenytoin
4. barbituates
5. rifampin
6. St. Johns Wort
Also chronic alcoholism (EtOH)

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