Flashcards in Nephrosis and Nephritis (4-5 star) Deck (19):
1
3 defining features of nephrotic syndrome
1. proteinuria over 3.5 g/day
2. hypoalbuminemia
3. peripheral edema
2
findings in nephritic syndrome
1. hematuria
2. RBC casts
3. renal failure symptoms--> oliguria, azotemia, hypertension (due to salt retention)
3
linear pattern of IgG deposition on IF
Goodpasture's syndrome
4
lumpy-bumpy deposits of IgG, IgM, and C3 in mesangium
Acute post-strep glomerulonephritis
5
deposits of IgA in mesangium
Berger's disease (IgA nephropathy)
6
Anti-GBM abs, hematuria, hemoptysis
Goodpasture's
7
nephritis, deafness, catracts
Alport's syndrome
8
Crescent formation in glomeruli
Rapidly progressive glomerulonephritis
9
wire-loop appearance on LM
Diffuse proliferative glomerulonephtitis (lupus-nephritis; "wire-lupus")
10
MC nephrotic syndrome in children
Minimal change disease
*often follows URI
11
MC nephrotic syndrome in adults
Focal segmental glomerulonephritis
12
effacement of foot processes on EM
minimal change disease
13
nodular glomerulosclerosis
diabetic glomerulonephropathy
14
nephtotic syndrome associated with Hep B
membranoproliferative glomerulonephritis
15
nephrotic syndrome associated with HIV
Focal segmental glomerulosclerosis
16
EM: subendothelial humps and tram-track appearance
membranoproliferative glomerulonephritis
17
LM: segmental sclerosis and hyalinosis
Focal segmental glomerulonephritis
18
purpura on back of legs and arma, abdominal pain, IgA nephropathy
Henoch-schlonlein purpura
19