Nephrosis and Nephritis (4-5 star) Flashcards Preview

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Flashcards in Nephrosis and Nephritis (4-5 star) Deck (19):
1

3 defining features of nephrotic syndrome

1. proteinuria over 3.5 g/day
2. hypoalbuminemia
3. peripheral edema

2

findings in nephritic syndrome

1. hematuria
2. RBC casts
3. renal failure symptoms--> oliguria, azotemia, hypertension (due to salt retention)

3

linear pattern of IgG deposition on IF

Goodpasture's syndrome

4

lumpy-bumpy deposits of IgG, IgM, and C3 in mesangium

Acute post-strep glomerulonephritis

5

deposits of IgA in mesangium

Berger's disease (IgA nephropathy)

6

Anti-GBM abs, hematuria, hemoptysis

Goodpasture's

7

nephritis, deafness, catracts

Alport's syndrome

8

Crescent formation in glomeruli

Rapidly progressive glomerulonephritis

9

wire-loop appearance on LM

Diffuse proliferative glomerulonephtitis (lupus-nephritis; "wire-lupus")

10

MC nephrotic syndrome in children

Minimal change disease

*often follows URI

11

MC nephrotic syndrome in adults

Focal segmental glomerulonephritis

12

effacement of foot processes on EM

minimal change disease

13

nodular glomerulosclerosis

diabetic glomerulonephropathy

14

nephtotic syndrome associated with Hep B

membranoproliferative glomerulonephritis

15

nephrotic syndrome associated with HIV

Focal segmental glomerulosclerosis

16

EM: subendothelial humps and tram-track appearance

membranoproliferative glomerulonephritis

17

LM: segmental sclerosis and hyalinosis

Focal segmental glomerulonephritis

18

purpura on back of legs and arma, abdominal pain, IgA nephropathy

Henoch-schlonlein purpura

19

spike and domes on GBM due to electron dense subepithelial deposits

membranous nephropathy

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