Introducing Research Ethics Flashcards Preview

Medicine, Year 2, Block 12 (Neurological, Neuromuscular, and MSK Diseases) > Introducing Research Ethics > Flashcards

Flashcards in Introducing Research Ethics Deck (12):
1

Define "Research"

"A structured activity which is intended to provide new knowledge which is generalisable and intended for wider dissemination."

2

Give examples of Historical Atrocities which have motivated the development of research ethics

- Nazi medical experiments
- Willowbrook study
- Tuskegee syphillis study
- Alderhey
- Andrew Wakefield MMR scandal

3

Give examples of Social, Moral, Political tends which have motivated the development of research ethics

- Patient autonomy
- Related legislation
- Nuremberg code
- Helsinki declaration

4

Give examples of 6 principles which should be questioned when carrying out research?

Usefullness
Necessity
Risks
Consent
Confidentiality
Ethics approval

5

What is consent defined as?

Permission from a person before involving them in research projects

6

What two things must consent be?

Informed
Voluntary

7

What things should be included in Participant Information Sheets when conducting a study?

1. Purpose of study
2. What happens if I take part
3. Risks / benefit of taking part
4. What happens if study stops / goes wrong
5. How will privacy / confidentiality be respected
6. Is there an ethics review?

8

What does the phrase "voluntary" mean? 3 points

- Not putting pressure on person
- Not offering incentives i.e. money
- Not threatening

9

What 4 things can be offered to help facilitate consent?

1. Presentation of info
2. Summary of key points
3. Opportunity to ask questions
4. Time to decide, at least 24 hours

10

How is research in a clinical context kept confidential?

- If identifiable information / anonymised from NHS -> must be granted REC approval
- Must be coded, anonymised
- Must be stored securely

11

When is REC approval required?

For human tissue, information, or personal data

12

Why is REC approval required for handling of sensitive data? 4 points

- Protects participants & researchers from harm
- Minimises claims of negligence
- Protects integrity and NHS reputation
- Condition of grant funding