Critical Appraisals Flashcards Preview

Medicine, Year 2, Block 12 (Neurological, Neuromuscular, and MSK Diseases) > Critical Appraisals > Flashcards

Flashcards in Critical Appraisals Deck (9):

To study a disease prognosis, what is the best study design?

Cohort study


To study a disease aetiology, what is the best study design?

Cohort study
Population based cohort study


To study a disease treatment, what is the best study design?

RCTs and Systematic Reviews of RCTs


To study a disease diagnostic method, what is the best study design?

Cross-sectional analytic study


What are the positives of Systematic Reviews?

- Find results of studies with relevant inclusion / exclusion data
- Include unpublished work
- Includes ALL evidence
- Includes non-English work
- Increases sample size
- Indicates variation between studies
- Allows sub-group analysis
- Allows sensitivity analysis


In Medline searches, what does the asterisk (*) denote?



What is the definition of bias?

Systematic introduction of error which distorts results in a non-random way


What does the phrase "Study validity" mean?

Believe-ability / credibility of results


Outline the ten steps of the CASP checklist to Critically Appraise evidence

1. Clearly focused question?
2. Right type of study included?
3. Was all studies included?
4. Quality assessment tool?
5. If combined results, is this reasonable?
6. How are results presented?
7. Are results precise?
8. Can results apply to population?
9. Were all outcomes considered?
10. Should policy change because of this?