Men's Health - Benign Prostatic Hyperplasia Flashcards

(18 cards)

1
Q

What is Benign Prostatic Hyperplasia (BPH)?

A

Benign Prostatic Hyperplasia (BPH) is the enlargement of the prostate without the presence of malignancy.

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2
Q

How common is Benign Prostatic Hyperplasia (BPH)?

A

BPH affects approximately 40% of men over the age of 50 and 90% over the age of 90.

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3
Q

What are the signs and symptoms of BPH?

A

Signs and symptoms of BPH include urinary frequency, urgency, hesitancy, nocturia, incomplete evacuation, and terminal dribbling.

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4
Q

What diagnostic tests are used for prostate health?

A

Prostate diagnostics include Digital Rectal Examination (DRE), Prostate-Specific Antigen (PSA) blood test, ultrasound, and biopsy.

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5
Q

What does a raised PSA indicate?

A

A raised PSA indicates possible prostate enlargement or inflammation and is normally used as a screen for prostate cancer. Levels >4.0 ng/ml require further investigation.

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6
Q

What is the natural approach for managing BPH?

A

The natural approach includes focusing on zinc-rich foods, addressing stress, optimizing body weight, and avoiding bladder irritants like alcohol, caffeine, and fizzy drinks.

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7
Q

How can zinc help in managing BPH?

A

Zinc acts as a 5α-reductase inhibitor and has been found to correct mitochondrial apoptosis, affecting the growth and differentiation of prostate tissue.

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8
Q

What is the role of physical activity in BPH management?

A

Physical activity has been shown to have an inverse association with BPH, improving urinary symptoms and helping with nocturia.

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9
Q

What is Beta-sitosterol, and how does it help with BPH?

A

Beta-sitosterol, found in pumpkin seeds, saw palmetto, and nettle root, inhibits 5α-reductase and aromatase, helping to improve urinary symptoms and flow in BPH.

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10
Q

What are tissue salts, and how can they help with BPH?

A

Tissue salts like Calc fluor, Nat. mur., Nat. sulph., and Mag. phos. can support BPH management by promoting overall prostate health.

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11
Q

How can diet help in managing BPH?

A

A diet rich in plant foods, polyphenols, and antioxidants can inhibit 5α-reductase activity, reduce inflammation, and support prostate health.

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12
Q

What are some foods that help manage BPH?

A

Foods rich in polyphenols like tomatoes (lycopene), green tea (epigallocatechin gallate), flaxseeds (lignans), and apples (kaempferol) are beneficial for managing BPH.

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13
Q

What is the role of lycopene in BPH management?

A

Lycopene, found in tomatoes, inhibits 5α-reductase and interleukin-6 signaling, helping to prevent prostate cell proliferation and remodeling.

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14
Q

What supplements can help in managing BPH?

A

Supplements like selenium (200–600 mcg), reishi (3–9 g/day), vitamin D (optimize levels), and berberine (50–250 mg/day) can support prostate health and reduce hyperplasia.

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15
Q

How does selenium support prostate health?

A

Selenium is an essential antioxidant and may reduce hyperplasia, PSA levels, and irregularities in prostate nuclei.

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16
Q

How does reishi help with BPH?

A

Reishi, a medicinal mushroom, may inhibit 5α-reductase and reduce PSA levels, supporting prostate health in BPH.

17
Q

What is the role of vitamin D in managing BPH?

A

Vitamin D helps decrease prostate cell proliferation, especially when induced by DHT, IL-8, and IGF-1. It also has anti-inflammatory properties.

18
Q

How does berberine help in BPH management?

A

Berberine may reduce prostatic hyperplasia in BPH by inhibiting 5α-reductase, ERK, and NF-κB, and by supporting overall prostate health.