Men's Health - Benign Prostatic Hyperplasia Flashcards
(18 cards)
What is Benign Prostatic Hyperplasia (BPH)?
Benign Prostatic Hyperplasia (BPH) is the enlargement of the prostate without the presence of malignancy.
How common is Benign Prostatic Hyperplasia (BPH)?
BPH affects approximately 40% of men over the age of 50 and 90% over the age of 90.
What are the signs and symptoms of BPH?
Signs and symptoms of BPH include urinary frequency, urgency, hesitancy, nocturia, incomplete evacuation, and terminal dribbling.
What diagnostic tests are used for prostate health?
Prostate diagnostics include Digital Rectal Examination (DRE), Prostate-Specific Antigen (PSA) blood test, ultrasound, and biopsy.
What does a raised PSA indicate?
A raised PSA indicates possible prostate enlargement or inflammation and is normally used as a screen for prostate cancer. Levels >4.0 ng/ml require further investigation.
What is the natural approach for managing BPH?
The natural approach includes focusing on zinc-rich foods, addressing stress, optimizing body weight, and avoiding bladder irritants like alcohol, caffeine, and fizzy drinks.
How can zinc help in managing BPH?
Zinc acts as a 5α-reductase inhibitor and has been found to correct mitochondrial apoptosis, affecting the growth and differentiation of prostate tissue.
What is the role of physical activity in BPH management?
Physical activity has been shown to have an inverse association with BPH, improving urinary symptoms and helping with nocturia.
What is Beta-sitosterol, and how does it help with BPH?
Beta-sitosterol, found in pumpkin seeds, saw palmetto, and nettle root, inhibits 5α-reductase and aromatase, helping to improve urinary symptoms and flow in BPH.
What are tissue salts, and how can they help with BPH?
Tissue salts like Calc fluor, Nat. mur., Nat. sulph., and Mag. phos. can support BPH management by promoting overall prostate health.
How can diet help in managing BPH?
A diet rich in plant foods, polyphenols, and antioxidants can inhibit 5α-reductase activity, reduce inflammation, and support prostate health.
What are some foods that help manage BPH?
Foods rich in polyphenols like tomatoes (lycopene), green tea (epigallocatechin gallate), flaxseeds (lignans), and apples (kaempferol) are beneficial for managing BPH.
What is the role of lycopene in BPH management?
Lycopene, found in tomatoes, inhibits 5α-reductase and interleukin-6 signaling, helping to prevent prostate cell proliferation and remodeling.
What supplements can help in managing BPH?
Supplements like selenium (200–600 mcg), reishi (3–9 g/day), vitamin D (optimize levels), and berberine (50–250 mg/day) can support prostate health and reduce hyperplasia.
How does selenium support prostate health?
Selenium is an essential antioxidant and may reduce hyperplasia, PSA levels, and irregularities in prostate nuclei.
How does reishi help with BPH?
Reishi, a medicinal mushroom, may inhibit 5α-reductase and reduce PSA levels, supporting prostate health in BPH.
What is the role of vitamin D in managing BPH?
Vitamin D helps decrease prostate cell proliferation, especially when induced by DHT, IL-8, and IGF-1. It also has anti-inflammatory properties.
How does berberine help in BPH management?
Berberine may reduce prostatic hyperplasia in BPH by inhibiting 5α-reductase, ERK, and NF-κB, and by supporting overall prostate health.