Odontogenic Cysts and Tumors Flashcards Preview

Dental Pathology > Odontogenic Cysts and Tumors > Flashcards

Flashcards in Odontogenic Cysts and Tumors Deck (61)
Loading flashcards...

the most common developmental odontogenic cyst; originates secondary to the separation of the follicle from the crown of an unerupted tooth; enlargement occurs secondary to increased osmotic pressure within the lumen of the cyst

dentigerous cyst


M>F; 2nd and 3rd decades; mandibular 3rd molars most common, followed by maxillary canines; typically asymptomatic or a painless expansion; unilocular radiolucency; affected tooth may by displaced; may see root resorption of adjacent teeth

dentigerous cyst


soft tissue counterpart to the dentigerous cyst; occurs within the soft tissue overlying the alveolar bone

eruption cyst


under 10 years; typically involves mandibular molars; soft, translucent swelling of the gingival mucosa overlying an unerupted tooth

eruption cyst


traditionally, defined as a cyst that develops in place of a missing tooth; most are histologically diagnosed as odontogenic keratocyst

primordial cyst


distinct odontogenic cyst with specific histologic features and clinical behavior; arises from cell rests of the dental lamina; also associated with nevoid basal cell carcinoma syndrome

odontogenic keratocyst


M>F; 10-40 years; mandible>Maxilla; rarely cause expansion; unilocular to multilocular radiolucency

odontogenic keratocyst


not necessarily a clinical type of cyst, but an odontogenic cyst that microscopically has an orthokeratinized lining; markedly different clinical behavior from the odontogenic keratocyst

orthokeratinized odontogenic cyst


nonspecific; M>F; young adults; most involve the mandibular third molars; stratified squamous epithelium that exhibits a prominent layer of orthokeratin

orthokeratinized odontogenic cyst


autosomal dominant syndrome secondary to mutations in the patched (PTCH) tumor suppressor gene; high penetrance and variable expressivity; features multiple basal cell carcinomas of skin, odontogenic keratocysts, rib and vertebral anomalies, and intracranial calcifications

nevoid basal cell carcinoma syndrome (gorlin syndrome)


frontal and temporoparietal bossing; ocular hypertelorism; multiple and early basal cell carcinomas; palmar/plantar pitting; bifid ribs and other skeletal anomalies; calcified falx cerebri; multiple odontogenic keratocysts

nevoid basal cell carcinoma syndrome


superficial, keratin-filled cysts on the alveolar mucosa; arise from remnants of the dental lamina; similar in appearance (although not location) to Epstein's pearls and Bohn's nodules

gingival cyst of the newborn


maxilla>mandible; multiple small papules on the alveolar processes of neonates

gingival cyst of the newborn


soft tissue counterpart of the lateral periodontal cyst; derived from rests of the dental lamina; 5th-6th decade; mandibular canine-premolar area; blue to blue-gray dome-shaped swelling

gingival cyst of the adult


Developmental (not inflammtory) cysts that typically occurs along the lateral root surface; probably arises from rests of the dental lamina

lateral periodontal cyst


M>F; over age 30; mandibular canine-premolar area; well circumscribed radiolucency lateral to the root of a vital tooth (multilocular=botyroid)

lateral periodontal cyst


uncommon cyst, sometimes associated with other odontogenic tumors; if no cystic component is present, epithelial odontogenic ghost cell tumor or deninogenic ghost cell tumor is more appropriate

calcifying odontogenic cyst


avg. age 33; maxilla=mandible, often involving the maxillary incisor-canine region; may be peripheral; unilocular radiolucency, often with radiopaque structures within the lesion; most lesions are 2-4 cm; may see root resorption or divergence

calcifying odontogenic cyst


rare odontogenic cyst that shows features of glandular differentiation; also referred to as sialo-odontogenic cyst; the pathogenesis of this lesion is unknown; adults, mandible; strong predilection for the anterior portions of the jaws; may cross the midline

glandular odontogenic cyst


larger lesions capable of bony expansion; well-defined unilocular or multilocular radiolucency with a sclerotic rim; "hobnail" appearance to the luminal epithelial cells

glandular odontogenic cyst


may arise de novo or from malignant transformation of a pre-existing cyst or neoplasm; must rule out the possibility of metastatic carcinoma

carcinoma arising in odontogenic cysts


M>F, older patients; pain, swelling, parasthesia; irregular, ragged radiolucency

carcinoma arising in odontogenic cysts


the most common of the odontogenic epithelial neoplasms; arises from odontogenic epithelium



M=F, avg, age 34; asymptomatic swelling and expansion; posterior mandible; multilocular radiolucency, often associated with an unerupted tooth; resorption of roots is common

conventional ameloblastoma


ameloblastoma _ variant: predilection for anterior regions of jaws; radiographic resemblance to fribro-osseous lesions



_ pattern of ameloblastoma: islands of epithelium resembling the enamel organ with peripheral palisading and reverse polarity; central area resembling stellate reticulum



_ pattern of ameloblastoma: anastomosing cords or sheets of cells; peripheral palisading and reverse polarity



_ pattern of ameloblastoma: squamous metaplasia within the tumor islands; keratin formation with occasional keratin pearls



_ pattern of ameloblastoma: cells within the islands are characterized by a granular cytoplasm

granular cell


_ pattern of ameloblastoma: small islands and cords of odontogenic epithelium; dense fibrous stroma