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Flashcards in Skin Diseases Deck (68)
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1

heterogenous group of disorder with different prognoses; characterized by blisters, ulcer, or erosions of skin, mucosa, or both; many with immunological etiology

vesiculobullous diseases

2

superficial skin infection (s. pyogenes and s. aureus); most common in children with poor hygeine, crowded living conditions and hot and humid climates

impetigo

3

arises in areas of trauma; multiple vesicles that rupture, leaving a honey-colored crust

impetigo

4

common chronic mucocutaneous disease; probably immune-mediated; may have only skin, only oral, or both; skin lesions- purple, polygonal, pruritic papules

lichen planus

5

reticular or erosive oral lesions; reticular-interlacing white lines, buccal mucosa; erosive-ulcers with erythema and white streaks

lichen planus

6

hyperkeratosis; degeneration of basal cell layer; "saw-toothed" rete ridges

lichen planus

7

"band-like" infiltrate of lymphocytes

lichen planus

8

shaggy band of fibrinogen at basement membrane zone seen with direct immunofluorescence

lichen planus

9

drug of choice for lichen planus

betamethasone gel

10

chronic skin disease characterized by an increase in the proliferative activity of keratinocytes; both genetic and environmental factors

psoriasis

11

2nd decade, waxing and waning course with lesions improving during the summer; scalp, elbows, knees

psoriasis

12

erythematous plaques with silvery scales

psoriasis

13

marked hyperparakeratosis; elongated rete ridges; perivascular inflammation; munro abscesses

psoriasis

14

PUVA (treatment for psoriasis) stands for

psoralen and ultraviolet A

15

hetergeneous group of inherited blistering mucocutaneous disorders; autosomal dominant or recessive; 3 broad categories: Simplex, Junctional, Dystrophic

epidermolysis bullosa

16

which form of epidermolyis bullosa?: vesicles/bullae that become ulcers and erosions that heal with scarring; gingival erythema, recession and reduction in vestibular depth

dominant dystrophic

17

which form of epidermolysis bullosa?: much more serious; secondary infection; mitten deformity; microstomia

recessive dystrophic

18

Intraepithelial clefting

epidermolysis bullosa (simplex)

19

subepithelial clefting (lamina lucida or lamina densa)

epidermolysis bullosa (junctional and dystrophic)

20

increased incidence of cutaneous squamous cell carcinoma

epidermolysis bullosa

21

acute, self-limiting ulcerative disorder, probably immune-mediate; 50%-unknown, 25%-drugs, 25%-herpes

erythema multiforme

22

EM- skin or mucosa only

erythema multiforme minor

23

EM (Stevens-Johnson syndrome)- at least two mucosal sites plus skin involvement

erythema multiforme major

24

EM- Lyell's disease

toxic epidermal necrolysis

25

young adults; may experience prodrome; hemorrhagic crusting of lips; widespread oral ulcers with ragged margins; labial, buccal mucosa and tongue; "target" lesions of skin

EM

26

diffuse sloughing of the skin and mucosa; older patients

toxic epidermal necrolysis

27

destruction of keratinocytes; subepithelial edema; mixed inflammatory infiltrate; perivascular inflammation

EM

28

benign lesion associated with HPV types 2,4 and 40; relatively contagious, with potential for autoinoculation

verruca vulgaris (common wart)

29

most commonly in children; skin of hands; more commonly sessile; variable color, but typically white

verruca vulgaris

30

papillary, hyperkeratotic proliferation of epithelium; rete ridges appear to converge toward the center of the lesion; course keratohyaline granules

verruca vulgaris