Flashcards in Skin Diseases Deck (68)
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1
heterogenous group of disorder with different prognoses; characterized by blisters, ulcer, or erosions of skin, mucosa, or both; many with immunological etiology
vesiculobullous diseases
2
superficial skin infection (s. pyogenes and s. aureus); most common in children with poor hygeine, crowded living conditions and hot and humid climates
impetigo
3
arises in areas of trauma; multiple vesicles that rupture, leaving a honey-colored crust
impetigo
4
common chronic mucocutaneous disease; probably immune-mediated; may have only skin, only oral, or both; skin lesions- purple, polygonal, pruritic papules
lichen planus
5
reticular or erosive oral lesions; reticular-interlacing white lines, buccal mucosa; erosive-ulcers with erythema and white streaks
lichen planus
6
hyperkeratosis; degeneration of basal cell layer; "saw-toothed" rete ridges
lichen planus
7
"band-like" infiltrate of lymphocytes
lichen planus
8
shaggy band of fibrinogen at basement membrane zone seen with direct immunofluorescence
lichen planus
9
drug of choice for lichen planus
betamethasone gel
10
chronic skin disease characterized by an increase in the proliferative activity of keratinocytes; both genetic and environmental factors
psoriasis
11
2nd decade, waxing and waning course with lesions improving during the summer; scalp, elbows, knees
psoriasis
12
erythematous plaques with silvery scales
psoriasis
13
marked hyperparakeratosis; elongated rete ridges; perivascular inflammation; munro abscesses
psoriasis
14
PUVA (treatment for psoriasis) stands for
psoralen and ultraviolet A
15
hetergeneous group of inherited blistering mucocutaneous disorders; autosomal dominant or recessive; 3 broad categories: Simplex, Junctional, Dystrophic
epidermolysis bullosa
16
which form of epidermolyis bullosa?: vesicles/bullae that become ulcers and erosions that heal with scarring; gingival erythema, recession and reduction in vestibular depth
dominant dystrophic
17
which form of epidermolysis bullosa?: much more serious; secondary infection; mitten deformity; microstomia
recessive dystrophic
18
Intraepithelial clefting
epidermolysis bullosa (simplex)
19
subepithelial clefting (lamina lucida or lamina densa)
epidermolysis bullosa (junctional and dystrophic)
20
increased incidence of cutaneous squamous cell carcinoma
epidermolysis bullosa
21
acute, self-limiting ulcerative disorder, probably immune-mediate; 50%-unknown, 25%-drugs, 25%-herpes
erythema multiforme
22
EM- skin or mucosa only
erythema multiforme minor
23
EM (Stevens-Johnson syndrome)- at least two mucosal sites plus skin involvement
erythema multiforme major
24
EM- Lyell's disease
toxic epidermal necrolysis
25
young adults; may experience prodrome; hemorrhagic crusting of lips; widespread oral ulcers with ragged margins; labial, buccal mucosa and tongue; "target" lesions of skin
EM
26
diffuse sloughing of the skin and mucosa; older patients
toxic epidermal necrolysis
27
destruction of keratinocytes; subepithelial edema; mixed inflammatory infiltrate; perivascular inflammation
EM
28
benign lesion associated with HPV types 2,4 and 40; relatively contagious, with potential for autoinoculation
verruca vulgaris (common wart)
29
most commonly in children; skin of hands; more commonly sessile; variable color, but typically white
verruca vulgaris
30
