peds20 Flashcards
(199 cards)
1
Q
def of CHF
A
inadequate ox delivery by the myocardium to meet the demands of the body
2
Q
what do the kidneys do during CHF?
A
retain salt and water as an attempt to increase blood volume because the kidneys are being hypoperfused
3
Q
catecholamines and CHF?
A
they are released to incr heart rate
4
Q
how does incr pulm blood flow cause CHF?
A
it’s just not what your heart is made to do; examples are VSD, PDA, transp of great arteries, truncus arteriosus, and total anomalous pulm venous conneciton
5
Q
what obstructive lesions cause CHF?
A
severe aortic, pulm, and mitral valve stenosis, coarctation of the aorta, interrupted aortic arch, and hypoplastic left heart syndrome
6
Q
infectious cause of CHF?
A
viral myocarditis (common in older kids), endocarditis, pericarditis,
7
Q
evidence of pulmonary congestion
A
tachypnea, cough, wheezing and rales
8
Q
evidence of impaired myocardial performance
A
tachycardia, sweating, pale or ashen skin, diminished urine output, and enlarged cardiac sillohuette on cxr
9
Q
hepatomegaly and peripheral edema are evidence of what?
A
systemic venous congestion
10
Q
late manifestations of CHF
A
cyanosis and shock
11
Q
three types of drugs used for CHG
A
cardiac glycosides, loop diuretics, inotropes
12
Q
how do cardiac glycosides work?
A
increase calcium-induced calcium release and therefore the force of contraction
13
Q
example of cardiac glycoside
A
digoxin
14
Q
ethacrynic acid
A
loop diuretic
15
Q
how do inotropes work?
A
increase heart contractility
16
Q
examples of inoropes
A
dobutamine, dopamine
17
Q
how do phosphodiesterase inhib help CHF?
A
improve contractility and reduce afterload
18
Q
balloon valvuloplasty used for what?
A
critical aortic and pulm valve stenosis
19
Q
what percent of kids have an innocent heart murmur?
A
50%
20
Q
still’s murmur age, location, and characteristics
A
age 2-7 years; mid-left sternal border; grade 1-3 systolic vibratory or buzzing; loudest supine and louder with exercise
21
Q
pulmonic systolic murmur (systolic ejection murmur)
A
any age; upper left sternal border; grade 1-2, peaks in early systole; blowing, high-pitched, loudest supine and louder with exercise
22
Q
venous hum- age, location, and characteristics
A
any age, but esp school age; neck and below the clavicles; continuous murmur, heard only sitting or standing; disappears if supine; changes with compression of the jugular vein or with neck flex or extension
23
Q
ostium primum
A
ASD in the lower portion of the atrial septum. Often associated with cleft or division in the ant mitral valve leaflet and cause mitral regurg
24
Q
ostium primum more common in what population?
A
down syndrome
25
ostium secondum
ASD in the middle portion of the atral septum. Most common type of ASD
26
sinus venosus
ASD high in the septum near the junction of the right atrium and SVC. The right pulm vein drains anomalously into the right atrium or SVC instead of into the left atrium
27
symptoms of acyanotic heart disease
minimal; incr RV impulse, systolic ejection murmur (from excessive pulm blood flow)at mid and upper left sternal borders; mid-diastolic murmur and fixed split second heart sound
28
how does acyanotic heart disease cause mid-diastolic filling rumble
excessive blood flow through the tricuspid valve
29
how does acyanotic heart disease cause fixed-split heart sound?
excessive pulm blood flow causes the the normal variation in timing of aortic and pulm valve closure with resp to be absent
30
VSD murmur?
high pitched holosystolic murmur at LLSB and thrill at LLSB; as the size of the VSD decreases, the intensity of the murmur increases
31
PDA murmur
continuous "machinery like" murmur at ULSB; brisk pulses; diastolic rumble of blood across mitral st the apex;
32
phys exam fininds in coarctation of aorta
elevated BP in right arm, reduced BP in legs, delayed and dampened fem pulse; bruit left upper back
33
aortic stenosis murmur
ejection click; systolic ejection murmur at base with radiation to URSB, apex, suprasternal notch and carotids; thrill at URSB and suprasternal notch
34
murmur with pulm stenosis?
ejection click; systolic ejection murmur at ULSB
35
ECG findings in VSD
normal or mild LVH; RVH if pulm htn present
36
ecg findings in PDA
LVH; RVH if pulm htn present
37
ecg finding in coarctation of the aorta
normal or LVH
38
aortic stenosis findings on ECG
normal or LVH
39
pum stenosis finding on ecg
RVH
40
ASD finding on ecg?
right axis dev, rvh, and right atrial enlargement
41
small VSD prognosis?
may close spontaneously
42
what if VSD with 2:1 ul to systemic blood flow?
diastolic murmur of mitral turbulence (excess blood from lungs now passing through the mitral valve) heard at apex
43
eisenmenger syndrome
ehn PVR exceeds SVR and shunting shifts to R to L
44
ductus arteriosis
connects pulm art to aorta
45
management of PDA
indomethacin, can be closed surgically by coil embolization, thorascopic surgery, and ligation in a thoracotomy
46
coarctation of the aorta
narrowing of the aortic arch just below the origin of the left subclavian artery and typically at or just proximal to the ductus arteriosus
47
neonates with open PDA and coarctation
depend on R to L shuntthroug the PDA for perfusion of the lower thoracric and descending aorta; sx develop when the PDA closes
48
findings in older kids with coarctation of aorta
hypertension in right arm and bp reduced in lower extremities; radiofemoral delay
49
other findings in coarctation of the aorta
bicuspid aortic valve or aortic stenosis is present in half of kids (if either is present, you have systolic murmur); bruit through the coarctation may be heard at the LU back near the scapula
50
management of coarctation of the aorta
improve circulation to the lower body by IV prostaglandin E to open the DA, then inotropic meds; surgery but recurrence Is common so balloon angioplasty is the choice
51
aortic stenosis in the neonate may lead to what?
hypoplasia of the LV as a result of impaired fetal left ventricular development
52
initial management of aortic stenosis
balloon valvuloplasty, then surgery for aortic valve replacement (Russ procedure) after 5-10 yrs after palliative valvuloplasty bc of recurrent stenosis
53
ross procedure
aortic valve is replaced with the patient's own pulm valve
54
most common cardiac causes of central cyanosis
the 5 Ts: tetrology of fallot, tranposiiton of the great arteries, tricuspid atresia, truncus arteriosis, and total anomalous pulm venous connection
55
100% oxygen challenge test suggest cyanotic CHD when?
when PaO2 fails to rise despite administration of 100% ox
56
tetrology of fallot
VSD, overriding aorta, pulm stenosis, and RV hypertrophy
57
most common cause of central cyanosis
tetrology of fallot
58
murmor in tetrology of flalot?
systolic ejectrion murmur representing the pulm stenosis
59
what kinds of activities bring on cyanosis in a kid with tetrology of fallot?
things that decr SVR (exercise, vasodilation, volume depletion)or increase resistance through the RVOT (Crying, tachycardia)
60
Tet spells
sudden cyanosis and decr murmur intensity; caused by decr arterial ox sat, which increases resistance through the RVOT, resulting in incr R to L shunt
61
how does a kid deal with a tet spell?
squat; to incr venous return to the heart and incr SVR
62
management of tet of fallot?
surgical repair at 4-8 months old
63
some kids with tet of fallot who cannot undergo surgery right away get what?
palliative procedure to improve systemic saturation and encourage pulmonary growth; either modified Blalock-Taussig shunt or balloon pulm valvuloplasty
64
TGA
aorta arises from the RV and pulm art from the LV; in order to live, you must also have a VSD, ASD, PFO or PDA
65
physical exam in TGA
central cyanosis, single S2 and no murmur
66
management of TGA
initial management with PGE to improve ox sat by keeping the ductus patent; or emergent balloon atrial septostomy (rashkind procedure) that incr size of PFO or ASD
67
definitive repair of TGA
arterial switch operation; coronaries must also be incised and reimplanted
68
tricuspid atresia
plate of tissue on the floor of the right atrium; ASD or PFO is always present; whether or not a vsd is present determines the direction of blood flow
69
clinical signs of pulm atresia
single S2 (if intacts ventricular septum)
70
ECG finding in tricsupid atresia
left axis deviation, LVH, and right atrial enlargmenet
71
fontan procedure
flow from the IVC is directed into the pulm arteries; treatment for tricuspid atresia
72
glenn shunt
SVC is anastamosed to the right pulm artery
73
treatment for tricuspid atresia
glenn shunt and then fontan
74
truncus arteriosus
aorta and pulm artery originate from a common artery, the truncus; vsd is almost always present
75
pathophys of truncus
excessive blood flow to the lungs and CHF commonly develops; mixing of desat and sat blood occurs in the truncus so patients are mildly desat and sometimes cyanotic
76
murmur in truncus
systolic ejection mumur at the base from incr flow across the truncal vale; single S2; diastolic murmur across the mitral due to excessive pulm lood flow that returns to the LA
77
total anomalous pulm venous connection
pulm veins drain into the systemic venous side instead of the LA;
78
murmur in TAPVC
pulm murmur due to incr pulm blood flow
79
cardiomegaly with a snowman appearance
total anomalous pulm venous connection
80
most common cause of acquired heart disease in children in the US
kawasaki disease
81
most common cause of acquired heart disease worldwide
acute rheumatic fever
82
infective endocarditis
microbial infection of the endocardium (inside surface of the heart)
83
most endocarditis occurs in who?
80% in kids with anatomic defects of the heart; 50% of cases occur after cardiac surgery
84
bacteria that cause endocarditis
gram pos cocci (alpha hemolytic staph and strep)
85
rare causes of endocarditis
gram net and funghi
86
diagnosis of endocarditis
blood culture and ESR elevated
87
splinter hemorrhages
linear hemorrhages beneath the nails, seen in endocarditis
88
retinal hemorrhage
seen in endocarditis
89
osler's nodes
small, raised pink or blue swollen tender lesions on the palms, soles, or pads of the toes or fingers; sign of endocarditis
90
janeway lesions
small erythematous hemorrhagic lesions on the palms or soles; sign of endocarditis
91
roth's spots
ound or oval white spots seen in the retina; sign of endocarditis
92
rheumatoid factor
found in 50% of patients with endocarditis
93
how to see vegetations?
transesophageal echo is more sens than transthoracic echo
94
management of endocarditis
IV anitbmicrobials fr 4-6 weeks; not a medical emergency, so therapy can be withheld until you do cultures
95
who should get antibiotic prophylaxis for endocarditis for surgery?
al patients with structural heart disease except secundum ASD; all post-op cardiac surgery patients for 6 months; all post-op cardiac surgerypatients for an indefinite pd of time if any hemodynamic residua of the lesion remain
96
pericarditis
inflamm of the pericardial space
97
causes of pericarditis
infection, collagen vascular disease, uremia, and inflamm response after cardiac surgery
98
most common cause of pericarditis in kids
viruses like coxsackievirus, echovirus, adenovirus, influenza, parainfluenza, and EBV
99
purulent pericarditis
usually caused by bacterial infection like staph aureus and strep pneumo
100
patients with purulent pericarditis have a high incidence of what?
constrictive pericarditis
101
postpericardiotomy syndrome
occurs in up to 1/3 of patients whose pericardium has been opened for surgery; thought to be an autoimmune response to viral infx
102
possible consequence of pericarditis
cardiac tamponade
103
chest pain in pericardits?
most intense when supine and relieved when sitting upright
104
physical exam findingsin pericarditis
friction rub, distant heart sounds if effusion is large, pulsus paradoxus, hepatomegaly
105
rub
pericarditis or MI
106
pulsus paradoxus
abnormally large decrease in systolic bp during inspir
107
ecg in pericarditis MAY show
ST changes or low-voltage qrs complexes in patients with pericardial effusion
108
treatment for bacterial or viral pericarditis?
antibiotics or steroids/aspirin
109
myocarditis
common cause of sudden death in young athletes
110
etiology of myocarditis
viruses, esp enterovirus like coxsackievirus; bacteria, fungi, protozoa, autoimmune disease, kawasaki disease
111
bacteria that cause myocarditis
diptheria, strep pyogenes, staph aureus, tuberculosis
112
symptoms of myocarditis
resting tachycardia and muffled heart sounds;
113
labs in myocarditis
elevated ESR, creatinine kinase MB fraction, and CRP
114
management of myocarditis
largely supportive; use of ionotropes, etc. as needed; heart transplant as last resort
115
prognosis of myocarditis
variable; mortality 10-20% and is esp high in young infants and those with ventricular dysrhythmias
116
most common cause of dilated cardiomyopathy
idiopathic
117
other causes of cardiomopathy
viral myocarditis, mitochondrial abnormalities, carnitine def, nutritional def (selenium and thiamine), hypocalcemia, chronic tachydysrhythmia, anomalous origin of left coronary artery from the pulm artery (ALCAPA), meds (doxorubicin)
118
eval of cardiomyopathy
viral serologies and serum carnitine
119
ALCAPA can cause what?
infarction
120
hypertrophic cardiomyopathy
LVH in the absence of any disease known to cause it; most typical finidng is asymm septal hypertrophy
121
inheritance of hypertrophic cardiomyopathy
aut do n most cases
122
most common cause of sudden death in athletes
hypertrophic cardiomyopathy
123
phys exam findings for hypertrophic cardiomyopathy
harsh systolic ejection murmur at the apex that is accentuated with maneuvers that reduce LV volume like valsalva or standing (by reducing LV volume, they worsen the outflow obstruction)
124
findings on ECG for hypertrophic cardiomyopathy
LVH, ST-seg and T wave changes, LAD and abnormally deep and wide Q waves in the inferior and lateral leads
125
management of hypertrophic cardiomyopathy
only treat patients w symptoms; beta blockers of CCBs reduce the LVOT obstruction; surgical myomectomy; antiarrhythmic medications; dual chamber pacing; participation in competitive sports prohibited
126
restrictive cardiomyopathy
rigid ventricular walls that impair normal diastolic filling
127
etiology of restrictive cardiomyopathy
amyloidosis,inherited infiltrative disorders like Fabry disease, Gaucher disease, hemosiderosis, hemochromatosis
128
physical exam findings in restrictive cardiomyopahty
elevated central venous pressure leads to edema, hepatomegaly, and ascites
129
management of restrictive cardiomyopathy
reduce CVP with diuretics and improve diastolic compliance with beta blockers and CCBs
130
most common dysrhythmias of childhood
supraventricular tachy (most common), then heart block, and long QT syndrome
131
AV re-entrant tachycardia
retrograde conduction through an accessory path leads to SVT
132
AV node reentrant tachycardia
conduction abnormality occurs in diff pways within the AV node itself
133
Wolf-Parkinson white syndrome
when anterograde conduction occures through a bypass tract between the atria and ventricles
134
WPW associated with what?
sudden cardiac death
135
WPW on ecg?
delta wave (upslope of QRS with a short PR)
136
management of SVT
vagal maneuvers, IV adenosine, synchronized cardioversion, chronic med management, radiofrequency catheter ablation
137
vagal manuever that helps convert SVT to sinus rhythm
ice pack on face
138
primary med used to convert SVT to sinus rhythm
IV adenosine
139
chronic medical management of SVT
digoxin or propanolol
140
radiofrequency cathether ablation
used to destroy the accessory pway in SVT
141
heart blcok
delayed or interrupted conduction of sinus or atrial impulses to the ventricles
142
first degree heart block
prolongation of the PR interval
143
second degree AV block
type 1 and type 2
144
type 1 second degree AV block
aka wenkebach; progressive prolongation of the PR interval leading to failed AV conduction
145
type 2 second degree AV block
abrupt failure of AV conduction without progressive prolongation of the PR interval
146
third degree av block
complete block
147
congenital third-degree block associated with what patient pop?
children born to mothers with SLE
148
post-surgical AV block
as a result of cardiac surgery
149
what infection may be associated with AV block?
bacterial endocarditis
150
treatment of asymp AV block
cardiac pacemaker
151
why is long QT bad?
increases the risk of lethal ventricular arrhythmias known as torsades de pointes
152
different inheritance patterns of long qt syndrome
autosomal recessive is jervell-lang-nielsen syndrome; autosomal dom is romano-ward syndrome
153
which cause of long qt is associated with congenital deafness
jervell-lange-nielson
154
examples of drugs that prolong qt interval
phenothiazines, tricyclic antidepressants, erythromycin, tefenadine
155
phenothiazine
antipsychotic
156
terfenedine
antihistamine
157
most common cause of chest painin kids
pericarditis
158
rapid heart rate w absent p waves
superventricular tachycardia
159
difference between vesicles and pustules
vesicles are fluid filled and pustules are purulent filled
160
cyst
nodule filled with expressible material
161
wheals
cutaneous elevations caused by dermal edema
162
excoriations
linear erosions into the epidermis caused by fingernail scratches
163
fissures
linear cracks into the dermis
164
annular
configurated in a circle
165
arcuate
in half circles
166
distributions
generalized, acral (hands, feet, buttocks), confined to a dermatme
167
how can we identify fungal hyphae
add 10% koh
168
how do we identify scabies
examine under a microscope looking for mites, eggs, or feces
169
absorption through the skin of a kid
same as through the skin of an adult except premature infants because they have a thinner stratum corneum
170
hyperkeratosis
thickened skin
171
keratolytis
salicylic acids, urea, alpha hydroxy acids, and retinoic acid
172
destructive therapies (for warts, molluscum contagiosum)
high dose salicylic acid, podophyllin, 5-FU, cryotherapy, electrotherapy, and laser therapy
173
only low dose corticosteroids should be used where?why?
face and groin because these areas have thinner skin
174
local side effects of steroids
acne, hirsutism, folliculitis, striae (esp in axilla or groin), hyper- or hypopigmentation, atrophy, ecchymoses and telangiectasias, tachyphylaxis
175
tacrolimus ointment
immunomodulator used for atopic dermatitis
176
one to five percent sulfur
formulated with other meds, used for acne
177
tar
used for eczema and psoriasis
178
contact dermatitis
inflamm of the epidermis and superficial dermis secondary to direct contact with the skin by a sensitizing substance
179
two types of contact dermatitis
allergic contact dermatitis and primary irritant contacst dermatitis
180
allergic contact dermatitis
T cell mediated
181
common causes of allergic dermatitis
poison ivy, oak or sumac; nickel containing jewelry and belt buckles; topical lotions and creams, perfumes, soap
182
clincial features of allergic dermatitis
erythematous papules and vesicles
183
treatment of allergic dermatitis
topical steroids
184
primary irritiant contact dermatiits
substance irritates the skin (not an allergic reaction); reaction is dose-dependent unlike allergic dermatitis
185
most common type of primary irritant dermatitis
diaper dermatitis
186
secondary infection with what on diaper dermatitis?
candida albicans
187
clinical features of diaper dermaitis
erythema with papules on the upper thighs, buttocks, and genitourinary area WITHOUT involvement of the inguinal creases
188
involvement of the inguinal creases may suggest what
candida superinfection
189
seborrheic dermaitits predominantly affects who?
infants and adolescnets
190
seborrheic dermatitis
cause unknown maybe due to a yeast that lives in areas that overproduce sebum;
191
clinical features of seborrheic dermatitis
red scales and crust in areas with high numbers of sebaceous glands (scalp, face, chest, groin); skin lesions may be greasy
192
seborrheic capitus
aka cradle cap dermatitis limited to the scalp
193
management of seborrheic dermatitis
low potency topical steroids, anti-fungals, sulfur, zinc, or salycilic acid shampoos
194
ptyriasis rosea
uncommon before 5 years old but extremely common in late childhood and adolescence
195
atopic dermaitits
aka eczema
196
clinical features of pityriasis rosea
malaise/ache, then solitary large red lesion (herald patch) on the trunk or upper extremities present for 1-30 days; THEN oval red macules and papules erupt for 3-6 weeks from chin to midthigh in christmas tree distrib
197
are pityriasis rosea lesions pruritic?
in about 50% of cases
198
managemnet of pityriasis rosea
topical or systemic antihistamines; exposure to UV light may shorten the disease course
199
psoriasis in kids?
way more common in adults
