peds98

Question 1

what causes the majority of monospot neg cases of mono in older kids?

Answer 1

CMV

Question 2

what is the preferred method to dx EBV in kids younger than 4

Answer 2

EBV antibody titers; these are antibodies to viral capsid antigen, early antigen, and epstein barr nuclear antigen

Question 3

acute infection of EBV is diagnosed by finding elevatd levels of what antibody?

Answer 3

igM- VCA (viral capsid antigen) and absent EBNA, which do not appear until 2-3 months after acute infection

Question 4

therapy for EBV infection

Answer 4

supportive; corticosteroids are sometimes used for severe pharyngitis

Question 5

complications of mono

Answer 5

CN palsies, encephalitis, severe pharyngitis causing upper airway obstruction, amoxicillin assoc rash, splenic rupture, malignancy

Question 6

how does EBV mono cause amox-associated rash

Answer 6

kids are misdiagnosed with GABHS pharyngitis and prescribed amox; diffuse pruritic maculopapular rash one week after starting the abx; not an allergic reaction

Question 7

why should kids with mono be restricted from contact sports

Answer 7

risk of splenic rupture