peds43

Question 1

other features in alagille syndrome

Answer 1

cardiac disease, renal disease, eye anomalies, msk anomalies, growth failure, panc insuff, hypercholesterolemia

Question 2

wilsons diseae

Answer 2

may cause acute and chornic hep and liver filure

Question 3

viruses besides the hepatitis A-E that can cause hepatitis

Answer 3

EBV, varicell-zoster, HIV, HSV

Question 4

heo A transmission

Answer 4

fecal-oral (contaminated food and water)

Question 5

most common hep virus causing infection

Answer 5

hep a

Question 6

why is transmission scary?

Answer 6

because virus is shed in the stool 2-3 weeks before onset of symptoms and 1 week AFTER the onset of jaundice

Question 7

incub period for hep a

Answer 7

206 weeks

Question 8

infection clinical features?

Answer 8

asymp in majority of kids; jaundice rare;

Question 9

igM anti-HAV

Answer 9

present early and persisits for up to 6 monhts

Question 10

igG anti-HAV

Answer 10

also present early but confers lifelong immunity

Question 11

hep a is Rna

Answer 11

right

Question 12

hep b is dna

Answer 12

right

Question 13

transmission of hep b

Answer 13

perinatal, or exposure to infected blood or bodily secretions (tears, saliva, semen, feces, etc)

Question 14

incub for hep b

Answer 14

45-160 days

Question 15

symptoms of hep B

Answer 15

range from asymp to nonspec systemic illness to liver failure

Question 16

chronic hbv infection

Answer 16

most common in infants who acquired through the birth canal; have incr risk of hepatocellular carcinoma

Question 17

hbsAg

Answer 17

pathognomonic for active disease

Question 18

HbsAb

Answer 18

from vaccination or natural infection; it is protective

Question 19

HBcAb

Answer 19

natural infection and persisits lifelong

Question 20

HBeAg

Answer 20

rises very early in active infection and therefore useful in dx acute infection

Question 21

hep c- dna or rna?

Answer 21

rna

Question 22

transmission of hep c

Answer 22

perinatal or parenteral exposure

Question 23

clinical features of hep c infection?

Answer 23

acute is rarely symptomatic, whereas chronic may result in cirrhosis and hepatic fibrosis; chronic infection occurs in 80%

Question 24

hep D- dna or rna?

Answer 24

rna virus