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Flashcards in peds43 Deck (24):
1

other features in alagille syndrome

cardiac disease, renal disease, eye anomalies, msk anomalies, growth failure, panc insuff, hypercholesterolemia

2

wilsons diseae

may cause acute and chornic hep and liver filure

3

viruses besides the hepatitis A-E that can cause hepatitis

EBV, varicell-zoster, HIV, HSV

4

heo A transmission

fecal-oral (contaminated food and water)

5

most common hep virus causing infection

hep a

6

why is transmission scary?

because virus is shed in the stool 2-3 weeks before onset of symptoms and 1 week AFTER the onset of jaundice

7

incub period for hep a

206 weeks

8

infection clinical features?

asymp in majority of kids; jaundice rare;

9

igM anti-HAV

present early and persisits for up to 6 monhts

10

igG anti-HAV

also present early but confers lifelong immunity

11

hep a is Rna

right

12

hep b is dna

right

13

transmission of hep b

perinatal, or exposure to infected blood or bodily secretions (tears, saliva, semen, feces, etc)

14

incub for hep b

45-160 days

15

symptoms of hep B

range from asymp to nonspec systemic illness to liver failure

16

chronic hbv infection

most common in infants who acquired through the birth canal; have incr risk of hepatocellular carcinoma

17

hbsAg

pathognomonic for active disease

18

HbsAb

from vaccination or natural infection; it is protective

19

HBcAb

natural infection and persisits lifelong

20

HBeAg

rises very early in active infection and therefore useful in dx acute infection

21

hep c- dna or rna?

rna

22

transmission of hep c

perinatal or parenteral exposure

23

clinical features of hep c infection?

acute is rarely symptomatic, whereas chronic may result in cirrhosis and hepatic fibrosis; chronic infection occurs in 80%

24

hep D- dna or rna?

rna virus