Flashcards in Retroviruses Deck (29):
True or False: Viruses with an envelope have poor survival outside the host.
Are feline retroviruses RNA or DNA viruses?
Which subtypes of FIV predominate in North America?
A and B
Transmission of FIV is mainly through what?
What are the 4 risk factors of FIV?
1. Older male
2. Outdoor access
3. History of fighting
4. FeLV infection
How long does the acute phase of FIV last?
During the acute phase of FIV, where does the virus replicate?
True or False: There is no viremia associated with the acute phase of FIV.
FALSE - there is a short viremic period.
During the acute phase of FIV, you may see a decrease in what cell lines?
1. CD4 T cells
2. CD8 T cells
What is the most consistent gastrointestinal signs of FIV?
True or False: During the subclinical phase of FIV it is difficult to recognize virus in the blood.
What does the ELISA test for FIV test for?
True or False: Because the FIV ELISA test tests antibody levels, false positives can be a problem.
What are 2 scenerios when you might get a false positive with an FIV ELISA?
1. Kitten < 6 weeks (due to maternal antibodies)
2. FIV-vaccinated cat
In what 5 specific scenarios should you test for FIV?
1. New cat
2. Sick cat
3. Possible exposure to FIV
4. Blood donor cat
5. Prior to FIV vaccination
What do you do with a positive FIV cat < 6 months of age?
Retest again in 60 days and up until 6 months of age. You cannot consider that cat FIV positive until 6 months of age.
With an FIV infection, how would your globulins be affected?
Globulins would be increased
With an FIV infection, how would your urine sample be affected?
Which clades is the FIV vaccine against?
A and D
True or False: There is no difference in mean survival time of FIV (+) and FIV (-) cats.
What are the 3 subgroups of FeLV most commonly seen?
Which subgroup of FeLV is infectious?
Only subgroup FeLV-A
What is the main mode of transmission of FeLV?
Licking and grooming/shared food and water bowels
What are the 3 risk factors of FeLV?
1. FIV infection
2. Access to outdoors
3. Contact with other cats
What are the 4 types of FeLV infections?
Which of the 4 types of FeLV infections test negative on antigen tests?
Abortive & Focal
How are the abortive and focal FeLV infections different?
Abortive - a robust immune response clears the virus
Focal - proviral DNA remains present in some tissues
Which type of FeLV infection has active replication and shedding?