Section 27 Flashcards

(40 cards)

1
Q

What is the primary goal of emergency management in poisoning?

A

To prevent further absorption, enhance elimination, and provide supportive care.

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2
Q

What are the common routes of poisoning exposure?

A

Ingestion, inhalation, dermal contact, and injection.

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3
Q

How is the airway managed in toxicology emergencies?

A

Ensure patency, provide oxygen, and consider intubation if necessary.

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4
Q

What is the role of activated charcoal in poisoning cases?

A

To absorb toxins in the gastrointestinal tract and reduce systemic absorption.

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5
Q

When is gastric lavage indicated in poisoning cases?

A

In life-threatening ingestions if performed within one hour of exposure.

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6
Q

What is the antidote for acetaminophen (paracetamol) poisoning?

A

N-acetylcysteine (NAC).

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7
Q

How is opioid overdose managed in emergency settings?

A

Administration of naloxone, airway support, and monitoring of respiratory function.

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8
Q

What is the first-line treatment for benzodiazepine overdose?

A

Flumazenil, though it is used cautiously due to risk of seizures.

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9
Q

What are the symptoms of organophosphate poisoning?

A

Salivation, lacrimation, urination, diarrhea, gastrointestinal distress, and emesis (SLUDGE).

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10
Q

How is organophosphate poisoning managed?

A

Administration of atropine and pralidoxime, along with decontamination.

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11
Q

What is the clinical presentation of carbon monoxide poisoning?

A

Headache, dizziness, confusion, cherry-red skin, and altered mental status.

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12
Q

How is carbon monoxide poisoning treated?

A

High-flow oxygen and hyperbaric oxygen therapy in severe cases.

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13
Q

What are the signs of methanol poisoning?

A

Metabolic acidosis, visual disturbances, and central nervous system depression.

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14
Q

How is methanol poisoning managed?

A

Administration of fomepizole or ethanol and hemodialysis if severe.

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15
Q

What are the clinical features of cyanide poisoning?

A

Rapid onset of headache, confusion, seizures, and cardiovascular collapse.

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16
Q

What is the antidote for cyanide poisoning?

A

Hydroxocobalamin or sodium thiosulfate.

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17
Q

How is iron overdose treated in emergency care?

A

Chelation therapy with deferoxamine and supportive care.

18
Q

What are the symptoms of salicylate poisoning?

A

Tinnitus, hyperventilation, metabolic acidosis, and dehydration.

19
Q

How is salicylate poisoning managed?

A

Alkalinization of urine, supportive care, and hemodialysis if severe.

20
Q

What are the indications for hemodialysis in poisoning?

A

Severe toxicity, impaired renal function, and poor response to supportive care.

21
Q

How is ethylene glycol poisoning identified?

A

Severe metabolic acidosis, renal failure, and calcium oxalate crystals in urine.

22
Q

What is the antidote for ethylene glycol poisoning?

A

Fomepizole or ethanol, along with hemodialysis if indicated.

23
Q

What are the symptoms of serotonin syndrome?

A

Hyperthermia, agitation, tremor, and autonomic instability.

24
Q

How is serotonin syndrome managed in emergency care?

A

Discontinuation of serotonergic agents, supportive care, and benzodiazepines if needed.

25
What are the key symptoms of tricyclic antidepressant overdose?
Cardiotoxicity, widened QRS complex, and anticholinergic effects.
26
How is tricyclic antidepressant overdose treated?
Sodium bicarbonate administration and supportive care.
27
What is the presentation of digoxin toxicity?
Nausea, vomiting, visual disturbances, and cardiac arrhythmias.
28
How is digoxin toxicity managed?
Administration of digoxin-specific antibody fragments (Digibind).
29
What are the clinical signs of beta-blocker overdose?
Bradycardia, hypotension, and potential cardiac arrest.
30
How is beta-blocker toxicity managed?
Administration of glucagon, high-dose insulin therapy, and supportive care.
31
What are the symptoms of calcium channel blocker overdose?
Severe hypotension, bradycardia, and cardiac conduction delays.
32
How is calcium channel blocker toxicity managed?
IV calcium, high-dose insulin, and vasopressors if necessary.
33
What is the role of whole-bowel irrigation in poisoning cases?
To flush out undigested toxins from the gastrointestinal tract.
34
How is arsenic poisoning identified?
Symptoms include vomiting, abdominal pain, diarrhea, and garlic-like breath odor.
35
How is arsenic poisoning managed?
Chelation therapy with dimercaprol or succimer.
36
What is the management approach for pesticide poisoning?
Decontamination, supportive care, and specific antidotes if available.
37
How is heavy metal poisoning detected?
Blood and urine tests for metals like lead, mercury, and arsenic.
38
How is lead poisoning managed?
Chelation therapy with EDTA or dimercaprol.
39
What is the role of urine alkalinization in toxicology?
To enhance the elimination of toxins like salicylates and phenobarbital.
40
How is mercury poisoning treated?
Chelation with dimercaprol or succimer, and supportive care.