Flashcards in Set 12 Lipoproteins Deck (24):
What are the lipoproteins?
chylomicron, VLDL, LDL, and HDL
What is the source for chylomicron?
What organ is the source for VLDL, LDL, and HDL?
What is the bad lipoprotein?
What is the function of chylomicron?
transports dietary lipids to the body
What is the function of VLDL?
transports endogenous lipids from liver to body
What is the function of LDL?
transports cholesterol from the liver to the body
What is the function of HDL?
removes excess "free" cholesterol from the blood
Where does beta oxidation occur?
How does beta oxidation work?
cuts chain two carbons at a time to make acetyl CoA for Kreb's
What does beta oxidation require? (To drive a FA in)
What does beta oxidation produce?
1 Acetyl CoA, reduces 1 FAD to FADH2, reduces 1 NAD to NADH
What is the final piece of beta oxidation when it starts with an odd numbered fatty acid chain?
propionyl CoA (3 carbons long)
What is ketogenesis?
forms ketone bodies as a by product of beta oxidation
What increases ketogenesis?
fasting, low carb diet, diabetes mellitus, and pregnancy (esp 3rd tri)
Where are ketones found?
breath and urine
What is the primary substrate for lipogenesis?
Where does lipogenesis occur?
What does lipegenesis produce?
fatty acids, two Cs at a time from Acetyl CoA
What is the most important intermediate of lipogenesis?
What does lipogenesis require?
Acetyl CoA, CO2 and NADPH
What stimulates lipogenesis?
ATP and insulin
What inhibits lipogenesis?
epinepherine and glucagon