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NBCE Part 1 > Set 12 Lipoproteins > Flashcards

Set 12 Lipoproteins Flashcards

1
Q

What are the lipoproteins?

A

chylomicron, VLDL, LDL, and HDL

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2
Q

What is the source for chylomicron?

A

intestinal mucosa

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3
Q

What organ is the source for VLDL, LDL, and HDL?

A

liver

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4
Q

What is the bad lipoprotein?

A

LDL

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5
Q

What is the function of chylomicron?

A

transports dietary lipids to the body

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6
Q

What is the function of VLDL?

A

transports endogenous lipids from liver to body

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7
Q

What is the function of LDL?

A

transports cholesterol from the liver to the body

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8
Q

What is the function of HDL?

A

removes excess “free” cholesterol from the blood

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9
Q

Where does beta oxidation occur?

A

mitochondria

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10
Q

How does beta oxidation work?

A

cuts chain two carbons at a time to make acetyl CoA for Kreb’s

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11
Q

What does beta oxidation require? (To drive a FA in)

A

carnatine

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12
Q

What does beta oxidation produce?

A

1 Acetyl CoA, reduces 1 FAD to FADH2, reduces 1 NAD to NADH

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13
Q

What is the final piece of beta oxidation when it starts with an odd numbered fatty acid chain?

A

propionyl CoA (3 carbons long)

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14
Q

What is ketogenesis?

A

forms ketone bodies as a by product of beta oxidation

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15
Q

What increases ketogenesis?

A

fasting, low carb diet, diabetes mellitus, and pregnancy (esp 3rd tri)

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16
Q

Where are ketones found?

A

breath and urine

17
Q

What is the primary substrate for lipogenesis?

A

acetyl CoA

18
Q

Where does lipogenesis occur?

A

cytoplasma

19
Q

What does lipegenesis produce?

A

fatty acids, two Cs at a time from Acetyl CoA

20
Q

What is the most important intermediate of lipogenesis?

A

malonyl CoA

21
Q

What does lipogenesis require?

A

Acetyl CoA, CO2 and NADPH

22
Q

What stimulates lipogenesis?

A

ATP and insulin

23
Q

What inhibits lipogenesis?

A

epinepherine and glucagon

24
Q

Where does lipid digestion occur?

A

mouth and small intestine (lingual lipase)

NBCE Part 1 (40 decks)

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