Set 24 Micro Immuno Flashcards Preview

NBCE Part 1 > Set 24 Micro Immuno > Flashcards

Flashcards in Set 24 Micro Immuno Deck (46):
1

What are the phagocytic cells of the immune system?

neutrophils, monocytes, and macrophages

2

What are the inflammatory mediator cells?

basophils, mast cells, eosinophils

3

What is the function of cytokines?

activate helper and cytotoxic T cells, kill pathogen or tumor cells

4

What is the function of NK cells?

can inactivate pathogens

5

What is the function of Killer T cells?

kill virus-infected cells by triggering target cell suicide

6

What is the function of Helper T cells?

help in antigen recognition and regulation

7

What do helper T cells secrete?

cytokines

8

What is an antigen?

target of antibodies and T cells

9

What is an epitope?

part of an antigen recognized by immune system

10

What is the function of CD4/Class I cells?

informs killer T cells of what is going on inside cells

11

What is the function of CD8/Class II cells?

informs helper T cells of problems outside cells

12

What is the function of an antibody?

tags an invader

13

What is Type I hypersensitivity?

immediate hypersensitivty (peanut, venom, penicilin) (outside in)

14

Which cells function in Type I hypersensitivity?

IgE, mast cells, basophils, allergic

15

Examples of Type I hypersensitivity:

anaphylaxis, hay fever, and asthma

16

What is Type II hypersensitivity?

antibody mediated (inside in)

17

Which cells function in Type II hypersensitivity?

IgG and IgM cause cell lysis

18

Examples of Type II hypersensitivity:

blood group incompatibility, pernicious anemia, myasthenia gravis

19

What is Type III hypersensitivity?

immune complex mediated (inside in)

20

Which cells function in Type III hypersensitivity?

IgG, antibody mediated inflammation, and some autoimmune

21

Examples of Type III hypersensitivity:

SLE, RA, serum sickness and rheumatic fever

22

What is Type IV hypersensitivity?

T cell mediated (outside in)

23

Examples of Type IV hypersensitivity:

infections, dermatitis, and graft rejections

24

When did SARS outbreak in China?

2002

25

When did bird flu outbreak in Asia?

2003

26

What is the most common food borne disease?

norovirus

27

What is the second most common food borne disease?

salmonella

28

How many new cases of TB?

8.8 mil

29

How many deaths from TB?

1.4 mil

30

What shape are bacilli?

rod shaped

31

What shape are cocci?

spherical

32

What shape are spirochetes?

spinal

33

What shape are spirilla?

spring

34

What is mutualism?

both benefit

35

What causes hay fever?

proteins from mold or plant spores

36

What causes asthma?

dust mites, cockroaches, rodents, and household pets

37

What is the process of asthma?

mast cells degranulate, histamine and other chemicals, IgE live 1 day, but weeks if attached to mast cells, basophils attach to IgE, and eosinophils have a chronic allergic reaction

38

What is Canale-Smith syndrome?

self reactive lymphocytes repeatedly stimulated, swollen lymph nodes

39

What is insulin-dependent diabetes mellitus?

organ specific immune disease - B cells target

40

What is myesthenia gravis?

self-reactive antibodies bind to ACh receptors

41

What is MS?

multiple sclerosis, CNS, self reactive T cells, myelin sheaths destroyed

42

What is the course of MS?

macrophages recruited by cytokines secreted by T cells, activated T cells can cross BBB

43

What is rheumatoid arthritis?

chronic joint inflammation

44

What is the course of RA?

IgM or IgG antibody activates macrophages, ^ inflammation

45

What is Lupus erythematosus?

red face rash, malar butterfly, inflammation of lungs, arthritis, kidney damage, hair loss, paralysis, and convultions

46

What causes Lupus Erythematosus?

breakdown of B and T cells that make IgG