3.4.1 Plasma Membrane: The Extracellular Matrix Flashcards
extracellular matrix
- an integrated network of carbohydrate and protein for support and cell communication
glycoproteins
- membrane proteins with carbohydrate chains covalently linked to amino acid side chains. This class of molecules includes collagen. Over half of our body’s proteins are comprised of collagen!
proteoglycans
- a family of glycoproteins that have a core polypeptide with numerous carbohydrate chains attached. Proteoglycans are high in carbohydrate, which may comprise as much as 95 percent of the weight of the
molecule
fibronectins
- a family of glycoproteins consisting of two polypeptides
linked by bonds. They bind matrix molecules to plasma membrane proteins.
actin filaments
- underneath the lipid bilayer bind to plasma membrane
proteins, adding further support to the extracellular matrix. - Cell signals are created by the physical perturbation of components of the matrix. It is hypothesized that certain forms of cancer may occur when errors in cell signals occur.
Which of the following is an example of a glycoprotein involved in the extracellular matrix?
- collagen
Which of the following statements regarding collagen is false?
a. Collagen is a glycoprotein.
b. Collagen is found outside the cell.
c. Collagen is bound to cytoskeletal components.
d. About half of the total protein in the human body is collagen.
- c. Collagen is bound to cytoskeletal components.
Integrins
- are plasma membrane proteins.
Which of the following is/are not found in animal cell membranes?
- nucleic acids
True or false?
On the inside of the cell, plasma membrane proteins involved with the extracellular matrix are anchored to fibronectins.
- false