Angina Flashcards Preview

Dental Pharmacology > Angina > Flashcards

Flashcards in Angina Deck (14):
1

only class to get vasodilation and venodilation

nitrates

2

venodilation results in decreased ...

preload

3

effect of nitrates on BP

unchanged or slight decrease

4

effect of nitrates on HR

unchanged or slight decrease

5

Do not take ... with nitrates because it increases cGMP by preventing metabolism, potential for augmented cGMP response to nitrates, profound hypotension, myocardial ischemia

sildenifil (viagra)

6

non-dihydropyridine CCBs

verapamil, diltiazem

7

dihydropyridine CCBs

nifedipine, felodipine

8

use-dependent binding (targets cardiac cells)

non-DHPs

9

voltage-dependent binding (targets vascular smooth muscle)

DHPs

10

which group?: blunts heart rate and inotropic response to exercise; reduces afterload; does not reduce preload; does not prevent coronary vasospasm

B blockers

11

abrupt ... of B blocker may induce rebound tachycardia: unstable angina or MI

withdrawal

12

B blockers are ineffective in the treatment of ...

vasospastic (prinzmetal's) angina

13

novel metabolic modulator; MoA is unknown; has ZERO hemodynamic effects; will not relieve acute angina attacks

Ranolazine

14

gingival inflammation

Ca channel blockers