Asthma and COPD Flashcards Preview

Dental Pharmacology > Asthma and COPD > Flashcards

Flashcards in Asthma and COPD Deck (28):
1

antiinflammatory drugs: inhaled steroids

budesonide; beclomethasone; fluticasone; mometasone; (ciclesonide)

2

antiinflammatory drug: modulator of mast cell degranulation; mast cell stabilizer

cromolyn

3

antiinflammatory drug: modulator of mast cell degranulation; anti-IgE

omalizumab

4

leukotriene modifiers: leukotriene receptor antagonists

montelukast; (zafirlukast)

5

leukotriene modifier: 5-LO (lipoxygenase) inhibitor

zileuton

6

bronchodilators: short acting B2 agonists

albuterol; (levalbuterol); (pirbuterol)

7

bronchodilators: long acting B2 agonists

salmeterol; formoterol; indacaterol

8

bronchodilators: methylxanthines

theophylline; aminophylline

9

bronchodilators: muscarinic receptor antagonists

ipratropium; tiotropium

10

bronchodilator: PDE-4 inhibitor

roflumilast

11

which bronchodilator should always be in your dental emergency kit?

albuterol

12

Which receptors?: located in large bronchioles; vagal innervation

cholinergic (M2) receptors

13

which receptors?: located in small bronchioles; no direct innervation

B2 receptors

14

anticholinergic: inhaler: response varies: increased broncho-selectivity by poor mucosal and CNS uptake

ipratropium bromide

15

anticholinergic: long duration of action: approved for COPD

tiotropium bromide

16

2 x daily dosing long acting B2 agonists

salmeterol; formoterol

17

1 x daily dosing long acting B2 agonist

indacaterol

18

theophylline and diethylamine

aminophylline

19

useful for allergic asthma; non-specific stabilizer of mast cell; inhibit cough by their action on airway nerves

cromolyn sodium

20

oral corticosteriods

methylprednisolone, prednisolone

21

"soft steroid"

ciclesonide

22

the most effective agents for acute attacks unresponsive to bronchodilators; restores B receptor therapy

oral or parenteral glucocorticoids

23

systemic effects of what?: decreased bone density in premenopausal women and decreased rate of growth in children

inhaled glucocorticoids

24

CYP2CP and 3A4 inhibited by ...

zafirlukast

25

receptor blockers?

"kasts"

26

synthesis blockers; inhibits leukotriene formation

zileuton

27

prophylaxis of moderate to severe aeroallergen associated asthma; prevents binding of IgE to a variety of cells (mast cells) associated with allergic response; SC injection

omalizumab

28

PDE4 inhibitor

roflumilast