IV Anesthetics Flashcards Preview

Dental Pharmacology > IV Anesthetics > Flashcards

Flashcards in IV Anesthetics Deck (28):
1

induction agents?

thiopental, etomidate, propofol, methohexital

2

Which tends to produce depressing effects in specific areas?

ketamine

3

which tends to produce global depressing effects?

thiopental

4

affect GABA system?

barbiturates, benzodiazepines, etomidate

5

affects glutamate system?

ketamine

6

bifunctional activity: GABA and glutamate?

propofol

7

which class prolongs binding of GABA to receptor?

barbiturates

8

which class causes an allosteric change in GABA receptor activity?

benzodiazepines

9

which drug is the exception and increases CBF, ICP, MAP, CO?

ketamine

10

which drug neither stimulates nor inhibits the cardiovascular system?

etomidate

11

a barbiturate so increased cytrochrome P450 activity (increase metabolic activity; enzyme induction); porphyria?

thiopental

12

anitemitic qualities (induce vomiting)?

propofol

13

inhibition of steroidogenesis; not used in ICU?

etomidate

14

analgesic; IM route; intact pharyngeal and laryngeal reflexes; bronchodilator for refractory asthma; hallucinations (may require w/ benzodiazepine)?

ketamine

15

dissociative agent: eyes open but unconscious and pain free?

ketamine

16

which class of drug: anticonvulsant; amnesia; wide safety margin; minimal CV and respiratory depression; useful where no analgesia required?

benzodiazepines

17

specific antagonist of benzodiazepines?

flumazenil

18

3 benzodiazipines?

diazepam; lorazepam; midazolam

19

half life of diazepam?

20-40

20

half life of lorazepam?

10-20

21

half life of midazolam?

2-4

22

opioid antagonists?

naloxone; nalmefene

23

opioid overdose triad?

pinpoint pupils; decreased respiration; coma

24

a new opioid class w/ potent analgesic activity, rapid onset, short half life; non cumulative effects; rapid recovery?

remifentanil

25

long lasting opioid?

morphine

26

opioid: more lipid soluble; peak effect in 2-3 min; nausea and vomiting rare?

fentanyl

27

in malignant hyperthermia, which receptor is affected by the drug to cause dramatic release of calcium

ryanodine receptor

28

antidote to malignant hyperthermia?

dantrium