Flashcards in IV Anesthetics Deck (28):
thiopental, etomidate, propofol, methohexital
Which tends to produce depressing effects in specific areas?
which tends to produce global depressing effects?
affect GABA system?
barbiturates, benzodiazepines, etomidate
affects glutamate system?
bifunctional activity: GABA and glutamate?
which class prolongs binding of GABA to receptor?
which class causes an allosteric change in GABA receptor activity?
which drug is the exception and increases CBF, ICP, MAP, CO?
which drug neither stimulates nor inhibits the cardiovascular system?
a barbiturate so increased cytrochrome P450 activity (increase metabolic activity; enzyme induction); porphyria?
anitemitic qualities (induce vomiting)?
inhibition of steroidogenesis; not used in ICU?
analgesic; IM route; intact pharyngeal and laryngeal reflexes; bronchodilator for refractory asthma; hallucinations (may require w/ benzodiazepine)?
dissociative agent: eyes open but unconscious and pain free?
which class of drug: anticonvulsant; amnesia; wide safety margin; minimal CV and respiratory depression; useful where no analgesia required?
specific antagonist of benzodiazepines?
diazepam; lorazepam; midazolam
half life of diazepam?
half life of lorazepam?
half life of midazolam?
opioid overdose triad?
pinpoint pupils; decreased respiration; coma
a new opioid class w/ potent analgesic activity, rapid onset, short half life; non cumulative effects; rapid recovery?
long lasting opioid?
opioid: more lipid soluble; peak effect in 2-3 min; nausea and vomiting rare?
in malignant hyperthermia, which receptor is affected by the drug to cause dramatic release of calcium