Biology Unit 5 Flashcards

(62 cards)

0
Q

Transcription

A

1st stage of protein synthesis. RNS strand is assembled from nucleotides using a gene iron in DNA as aTemplate

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1
Q

Epigenetic Inheritance

A

Inheritance if genes that have on/off capabilities based on their ancestors’ environmental experiments

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2
Q

Codon

A

The base triplets in mRNA

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3
Q

mRNA

A

Messenger RNA (linear or flat)

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4
Q

rRNA

A

Ribosomal (large glob)

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5
Q

tRNA

A

Transfer (t)

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6
Q

Step 1 of protein synthesis

A

RNA Synthase unzip DNA

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7
Q

Where do we get amino acids from?

A

Protein

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8
Q

Transcription

A

Synthesis of mRNA under the direction of DNA. occurs in the nucleus.

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9
Q

Translation

A

Actual decoding of the mRNA into a polypeptide. Occurs in ribosomes of cytoplasm and rough ER

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10
Q

Triplet code (codons)

A

The genetic instructions to obtain specific individual amino acids that form the polypeptide chai are “written” in the DNA as a series of 3 nucleotide “words”

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11
Q

RNA Polymerase

A

Copies DNA into RNA. Lays down a 5’ first so we use the 3’ strand of DNA

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12
Q

Antisense strand

A

3’ of DNA

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13
Q

Sense strand

A

5’ un copied of DNA

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14
Q

Promoter/initiation sequence

A

Start sequence

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15
Q

Terminator

A

Stop sequence

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16
Q

Any 3 types of RNA can be made during…

A

Transcription

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17
Q

pre-mRNA

A

mRNA rough draft

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18
Q

RNA Processing

A

Process of which we edit mRNA

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19
Q

Introns

A

Non-protein making regions of the pre-mRNA

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20
Q

3 Parts of mRNA Processing q

A

Introns removed, exons linked together, caps and tails added

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21
Q

3 parts of mRNA

A

Leader, reading frame, trailer

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22
Q

Formula to get a human protein

A

Codon + anticodon + inactive amino acid= human protein

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23
Q

tRNA’s 3 jobs

A

Provide the anticodon used for decoding nucleotide triplet, brings in the inactive amino acid, holds the growing polypeptide inside the factory

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24
A Site
Holds the tRNA carrying the amino acid to be activated and th
25
P Site
Holds the tRNA carrying the growing polypeptide chain
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E Site
Exit of tRNA one
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How can we increase efficiency of translation?
Multipl
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Polysomes
A complex of ribosomes strung along a single strand of mRNA that translates the genetic info in the mRNA during protein synthesis
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Mutation
Any change in the nucleotide sequence of an organism's DNA
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Point mutation
Changes in the genetic sequence that occur at specific points in the DNAstrand
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Base substitutions
Point mutations which 1 nitrogenous base is substituted by another
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Transitions
Base substitutions that swap purine for purine or pyrimidine for pyrimidine
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Purines
G A
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Transverse
Base substitutions that swap purine for pyrimidine or vise versa
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Insertions
Point mutations which 1 or more base pairs is added to DNA
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Deletion
A point mutation which 1 or more base pairs are removed
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Missense mutation
A point mutation which changes a codon to indicate a different amino acid
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Nonsense mutation
A point mutation that turns 1 codon into a stop codon results in early termination of the polypeptide chain
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Silent mutation
A point mutation that has no overall effect of a protein's function.
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Mutagen
Any chemical or physical agent that causes a mutation in DNA
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What does mutagen mean?
Origin of mutations
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Examples of mutagens
Heat, uv radiation, chemicals
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How many nucleotides are affected by mutagens?
1/1billion
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Reading frame
A way of dividing the mRNA into codons
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Frameshift mutation
Mutation caused by an insertion or deletion which causes a shift in the translational reading frame
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Law of dominance
Homozygous crosses only result in dominant traits
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Incomplete Dominance
Characterized by a blending of traits. Phenotype of offspring fall in between each other. EX red horses crossed with white horses
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Co-
.
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Epistasis
Characterized where 1 set of genes (2 alleles) controls a totally different set of alleles. Often the controlling alleles block the expression of others. EX Albinism
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Polygenics
Characterized by many genes are needed to affect a single trait EX hair color, eye color, skin color
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Sex Influenced
Genes that are expressed differently based on hormones produced by the sex hormones X or Y estrogen or testosterone EX Patterned baldness by testosterone
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Sex linkage
Characterized by genes carried on the X (x linked) and Y (holondric) chromosome EX hemophilia, ear hair, colorblindness
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Environmental Genes
(Epigenetics) phenotype that changes as genes are exposed to external stormill like temperature EX foxes and Siamese
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Pleiotropy
1 set of Genes control multiple outcomes EX Dalmations have genes for white coats color but also controls the ability to hear
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X-Inactivation
Since females have 2 X chromosomes, if each carries a regular dominant genes there could be a conflict so some genes become inactive EX Calico cats
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Law of Dominance
Some outcomes for a trait are dominant over other possible outcomes for that same trait
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Law of segregation
1/2 genes come from mom and 1/2 genes come from dad after meiosis and the creation of gametes
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Law of Independent Assortment
No genes for different traits are linked together and inherited together. There is no linkage.
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Pedigree
Used to illustrate phenotype through families but don't illustrate chromosomes or gene squeezes
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Karyotype
Shows overall large chromosome structure but not gene sequence. Autosomal verses sex chromosomes
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Cytological
Illustrates actual gene sequences of DNA. Used To determine point mutations