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Flashcards in Brain Imaging Lec10 Deck (60)
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1

____ imaging invovles a rotating x ray beam

CT

2

rate of attenuation with a CT varies by

tissue

Beam attenuates (ie weakens) as it passes through brain tissue

3

what is detected with a CT?

radiodensity information

used to reconstruct 3d image

4

advantages to CT

bone imaging

hemorrhage detection

patient flexibility

5

disadvantages to CT

1. ionizing radiation

2. not as good for soft tissue

3. lower spatial resolution

6

with MRI, Rapid repetitions of ___ enhance gray-white contrast

RF pulse 

7

with MRI,  Infrequent RF pulses enhance___

 water signal

8

advantages to MRI

1. high spatial resolution

2. no radiation

3. excellent contrast

4. functional/chemical imaing avail.

9

disadvantages to MRI

1. long study duration

2. no ferromagnetic or electronic devices

3. small as hell -- claustrophobia

10

with Magnetic resosnance spectroscopy you look at the

chemical structure of the brain

11

on MRS choline indicates

demyelination

12

on MRS, creatine indciates

glial

13

on MRS, lactate indicates

ischemia

14

on MRS, NAA indicates

neuronal marker

15

____ involves measuring water diffusion

DTI: Diffusion Tensor Imaging

16

DTI: Diffusion Tensor Imaging invovles measuring water diffusion along different orientatations within ___

axes

17

fMRI in vivo measures 

BOLD, blood-oxygen-level dependent, signals at baseline vs.
! experimental conditions

18

limitations of FMRI includes

spatial and temporal resolution

19

what does PET involves?

PET: radioactive tracer incorporated into a biologically active molecule (ex. Glucose, oxygen, dopamine transporters)

20

disadvantages of PET? 

 1. need a cyclotron to make radioisotope

2. radiation exposure

21

what are 5 applications of imaging mdoalities?

1. map nml brain development

2. alzheimers disease

3. image guieded neurosurgery

4. schizopehnia

5. pain )in high vs. low sensitvity pts)

22

advantages of pet?

functional imaging

physiological variables can be determined

23

to study brain structure what could you use

CT or MRI

24

what to use when looking at vascualture? 

MRI

25

what to use when looking at fiber tracts? 

mri

26

what to use when looking at brain perfusion? 

pet

27

what to use when looking at NT integrity? 

PET

28

what to use when looking at metabolism? 

PET

29

what to use when looking at chemical structure? 

MRI

30

elements of ___ atomic numbers show up better on CT

high (ca iron barium lead)