Basal Ganglia Lec22 Flashcards Preview

Neuroscience > Basal Ganglia Lec22 > Flashcards

Flashcards in Basal Ganglia Lec22 Deck (64)
Loading flashcards...
1

in the direct basal ganglia circuit 

the cortex has a ___ inputs on the striatum

excitatory

 

2

in the direct pathway the striatum sends ___ projections to the ____.

striatum inhbiitory to intenral globus pallidus

3

in the direct pathway

the intneral globus pallidus sends ___ projetions to the ___.

inhibitory projections to the thalamus

"the break"

4

when active, the direct pathway ___ the brake on the thalamic positive input on the cortex

inhibits

it removes the break

5

the ___ pathway turns the brake on 

indirect

6

in the indirect pathway

the cortex has a ____ projection to the striatum

excitatory 

7

in the indirect pathway

the striatum sends ____ projection to the ____

inhibitroy on the external globus pallidus

8

in the indirect pathway

the external globus pallidus sends ____ projection to the ____

inhibiotry projection to the subthalamic nculeus

9

in the indirect pathway

the subthalamic nucelus sends ____ projection to the ____

excitatory projection to the internal globus pallidus (which when activated inhibits the thalamus)

10

what is the mechanism in which the indirect pathway turns on the brake?

it removes inhibition on the inhibiotyr neuron (from the globus pallidus) acting on the subthalamic nucleus

which sitmulates the external globus pallidus

which inhibits the thalamus

11

most common basal ganglia neuron?

Medium Spiny Stellate Neuron

12

what do the Medium Spiny Stellate Neuron do?

Connect input and output portions of basal ganglia

13

medium spiny stellate neurosna re Mostly in the ___ & ACh(+)

matrix

14

some medium spiny stellate neurons are in the
____ & are ACh(-)

striosome

15

where are spindle neurons located

globus pallidus and STN

16

where in the thalamus do the spindle neurons project to?

va/vl

17

where in the globus pallidus does spindle neurons projec tto?

intenral GP

18

where do the pigmented neurosn project to?

striatum, GP, STN

19

inputs of striosome spiny stellate neurons?

limbic cortex and SNpc

20

outputs of strosome med. spiny stellate neurons

substantia nigra

21

inputs to matrix med. spiny stellate neurons

cortex, intenruons of substantia nigra

22

outputs of  matrix med. spiny stellate neurons

globus pallidus

23

output structures of the basal ganglia project back to the

thalamus first ebfore the cerbral cortex 

24

what keeps the basala ganglia chain moving?

dopamine supplied by the substantia nigra

25

inputs from the cortex go into the

caudate and the putamen

26

outputs from basal ganglia leave by the 

globus pallidus and substrantia nigra

27

 Dopamine enhances___pathway

 D1/direct 

28

doapmine inhibits___ pathway

 D2/indirect

29

dopamine causes ___ of the thalamus

disinhibition

30

dopamine promotes ___ receptors

D1