Nociception Flashcards Preview

Neuroscience > Nociception > Flashcards

Flashcards in Nociception Deck (56)
Loading flashcards...
1

Nociceptors exist as free nerve endings activated only when the stimulus is ___.

strong enough to cause damage. 

2

___ nociceptors have fast responses

thermal/mechanical

3

___ nociceptors are myelinated

thermal/mechanical

4

___ nociceptors are unmeylinated

polymodal

5

thermal/mechanical noiceptors are assocaited with ___ pain

sharp, prickling pain

6

polymodal nociceptors are assocaited with

with high intensity mechanical, chemical, hot, and cold stimuli.

7

Nociceptive specific neurons are found in___of the spinal cord

 Lamina 1 

8

nocipceptive specific neurons have ___ receptor fields

small

9

nocieptive specific neurons carry

only info about noceipcetion

10

. Wide dynamic range neurons (WDR) are found in ___ of the spinal cord

Lamina 5 

11

Wide dynamic range neurons  carry information

from both mechanoreceptors and noiceptors

12

Wide dynamic range neurons have ___ receptor fields

larger

13

. hyperalgesia is what happens when you have increased sensitivity to the ____.

surrounding unharmed region of a damaged area

14

with hyperalgesia Subsequent stimuli result in the 

enhanced sensation of pain 

15

referred pain is the result of a ____

 lack of nociceptive output neurons in the dorsal horn that are dedicated to visceral pain

16

dissociated sensory loss is when you have reduced sensation of epicritic sensation in the opposite side of the body from where you have ___.

reduced sensation of temperature and pain

17

Pain modulation can occur as the result of the descending pathway synapsing with 

an opiate containing interneuron

18

The opiate containing interneruon synapses with the ascending pathway in the dorsal horn releasing enkephalin that dampens 

both presynaptic and postsynaptic neurons

19

pain vs. noiception?

pain is a psychological perception

20

where are the cell bodies of noiceptors? 

located in the dorsal root and trigeminal ganglia.

21

Nociceptors exist as free nerve endings that do not have ___

peripheral structures

22

____ nociceptors have small-diameter, thinly myelinated A

thermal/mechanical

23

___ noiceptors have small- diameter, unmyelinated C fibers 

polymodal

24

 If the stimulus intensity is raised to a level that activates A

 tingling sensation

25

If the stimulus intensity is raised to a level that activates A

sharp pain

26

 If the stimulus intensity is increased further, so that the small-diameter, slowly conducting C fiber axons then a a ___ is experienced.

duller, longer-lasting sensation of pain

27

The vanilloid receptor TrpV1 is found in both___ fibers

 C and A

28

TRPv1 is Activated by stimuli such as (3)

capsaicin, heat, acids and anandamide

29

___ receptors may respond to endogenous chemicals similar to capsaicin that are released with peripheral injury

TrpV1

30

in the flare region following hyperalgesia, ___ drops dramatically

threshold sensitivity