Sleep Disorders CC6

Question 1

what do you need to have to be dx with sleep disorder?

Answer 1

must have next day consequences

Question 2

what do you need to LACK to be dx with a sleep disorder

Answer 2

ANY organic, psych, or substance etiology

Question 3

advanced circadian clock problems often involves what population

Answer 3

elderly people go to sleep and wake up early

Question 4

delayed circadian clock problems often involves what population

Answer 4

third shift work, jet lag

Question 5

what should you tx insomnia with

Answer 5

GABA, galanine, or psychotherapy

Question 6

what should you tx hypersomnia with

Answer 6

stimulants, antidepressants, or naps

Question 7

which sleep disorder has the strongest genetic ties?

Answer 7

narcolepsy

Question 8

cause of narcelopsy

Answer 8

caused by autoimmune destruction of orexin (“backup generator”) neurons

Question 9

hypnopompic hallucinations

Answer 9

hallucinations upon waking

Question 10

hypnogogic hallucinations

Answer 10

hallucinations uponm sleeping

Question 11

what is cataplexy often triggered by

Answer 11

strong emotions

Question 12

central sleep apnea involves

Answer 12

the brainstem stops working in sleep

Question 13

Obstructive sleep apnea is associated with loss of ___

Answer 13

muscle tone

Question 14

obstructive sleep apnea is associated with

Answer 14

age, high BP, and obesity.

Question 15

tx for sleep apnea

Answer 15

central psotiive airway pressure or dental devices

Question 16

what is not recommended for tx for sleep apnea

Answer 16

surgery

Question 17

cause of Restless Legs Syndrome?

Answer 17

combination of genes and environment

Question 18

low Fe can be a cause of

Answer 18

restless legs syndrome

Question 19

tx of restless leg syndrome?

Answer 19

dopamine

Question 20

sleep terrors occur during

Answer 20

3/4 sleep

Question 21

nightmare disorder occurs during

Answer 21

rem sleep

Question 22

Sleepwalking/Somnambulism occurs during

Answer 22

stage 3/4 sleep

Question 23

sleep talking occurs during

Answer 23

all sleep stages

Question 24

Sleep Related Bruxism occurs during

Answer 24

stage 2 sleep

Question 25

the ___ areas of the alteral hypothlaamus are the off switchand NREM promoting center of the CNS

Answer 25

ventrolateral and median preoptic

Question 26

VLPO/MNPO causes us to sleep via increased

Answer 26

gaba and galanin activity

Question 27

VLPO/MNPO turns off ___ TMN wakefulness half of the switch

Answer 27

histamine

Question 28

VLPO/MNPO are silent during

Answer 28

wakelfulness

Question 29

when does VLPO/MNPO fire?

Answer 29

during NREM

Question 30

___ fires mostly as one drifts to sleep

Answer 30

MNPO

Question 31

___ fires while asleep

Answer 31

VLPO

Question 32

gaba and galanin are inhbitiory transmitters with fibers proecting to

Answer 32

arousal centers (LC, PAG, LDT/PPT, DR, orexins)

Question 33

during NREM, serotonin, norepeinhepine, dopamine all fire supressing ___ alloing the porcess of sleep stage 1-4

Answer 33

acetylcholine

Question 34

adenosine build up inhbiits

Answer 34

wakefulness centers

Question 35

adenosine homeostsis increases while awake during

Answer 35

metabolism

Question 36

adenosine build up sitmulates

Answer 36

VLPO to cause sleep

Question 37

Sleep drive ___ the longer one stays awake.

Answer 37

increases

Question 38

lack oflight via eyes/optic nerve signals the ___ of the hypothlamaus for mealtonin release

Answer 38

suprhciasmatic

Question 39

melatonin can be supressed with

Answer 39

24 hour light

Question 40

CRY, CLOCK, BMAL1, PER1 are ___ genes

Answer 40

clock genes that control your circadian clock

Question 41

___ drive transcription of cry/per/pev-erba

Answer 41

clock/bmal1

Question 42

zeitgebers that modibfy our clock

Answer 42

melatonin, caffeine, alcohol

light

food

exercise

social interaction

Question 43

if I drank some coffee at 3pm, I would ____ my adenosine load and my brain would think it is noon allowing me to be less sleep.

Answer 43

lower

Question 44

insomnia is defined as difficult inaitiating or maintain sleep, early morning awkaening, non restorative sleep for

Answer 44

1 month

Question 45

sleep deprivation results in less activation in the

Answer 45

frontal lobe

Question 46

narcolepsy ivnovles daily sleepa ttackes for

Answer 46

3 months

Question 47

narcolepsy involves no ___ latency

Answer 47

rem

Question 48

circadian rhytm sleep disorder yeilds __ or ___ due to sleep wake cycle mismatch, shift, or synchrony

Answer 48

insomnia or hypersomnia

Question 49

___ circadian rhytm disorder involves falling asleep too early at night and waking too early

Answer 49

advanced

Question 50

circadian rhythm sleep disorder should be tx with

Answer 50

sleep scheduling, benzos, melatonin, exercise, stimulants or light therapy

Question 51

nocturnal myoclonus involves

Answer 51

iunconcious leg movements

this is now called periodic limb movement disorder

Question 52

___ involves concious leg movement and creeping sensations

Answer 52

restless legs

Question 53

you remember dream with ___ disorder

Answer 53

nightmare

Question 54

with nightmare disorder you awake

Answer 54

alert and oriented

Question 55

with sleep terror disorder you awake

Answer 55

disorented, not consolable

Question 56

sleep relatex bruxism is efined as

Answer 56

teeth grinding

Question 57

REM sleep behavior disorder is defined as

Answer 57

loss of atonia during rem (acting out dreams)

often violent, men act out dreams sometimes

Question 58

tx of REM sleep behavior disorder

Answer 58

d2 agonists