Sleep Disorders CC6 Flashcards Preview

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Flashcards in Sleep Disorders CC6 Deck (58):
1

what do you need to have to be dx with sleep disorder?

must have next day consequences

2

what do you need to LACK to be dx with a sleep disorder

ANY organic, psych, or substance etiology

3

advanced circadian clock problems often involves what population

elderly people go to sleep and wake up early

4

delayed circadian clock problems often involves what population

third shift work, jet lag

5

what should you tx insomnia with

GABA, galanine, or psychotherapy

6

what should you tx hypersomnia with

stimulants, antidepressants, or naps

7

which sleep disorder has the strongest genetic ties?

narcolepsy

8

cause of narcelopsy

caused by autoimmune destruction of orexin (“backup generator”) neurons

9

hypnopompic hallucinations

hallucinations upon waking

10

hypnogogic hallucinations

hallucinations uponm sleeping

11

what is cataplexy often triggered by

strong emotions

12

central sleep apnea involves

the brainstem stops working in sleep

13

Obstructive sleep apnea is associated with loss of ___

muscle tone

14

obstructive sleep apnea is associated with

age, high BP, and obesity.

15

tx for sleep apnea

central psotiive airway pressure or dental devices

16

what is not recommended for tx for sleep apnea

surgery

17

cause of Restless Legs Syndrome?

combination of genes and environment

18

low Fe can be a cause of

restless legs syndrome

19

tx of restless leg syndrome?

dopamine

20

sleep terrors occur during

3/4 sleep

21

nightmare disorder occurs during

rem sleep

22

Sleepwalking/Somnambulism occurs during

stage 3/4 sleep

23

sleep talking occurs during

all sleep stages

24

Sleep Related Bruxism occurs during

stage 2 sleep

25

the ___ areas of the alteral hypothlaamus are the off switchand NREM promoting center of the CNS

ventrolateral and median preoptic

26

VLPO/MNPO causes us to sleep via increased

gaba and galanin activity

27

VLPO/MNPO turns off ___ TMN wakefulness half of the switch

histamine

28

VLPO/MNPO are silent during

wakelfulness

29

when does VLPO/MNPO fire?

during NREM

30

___ fires mostly as one drifts to sleep

MNPO

31

___ fires while asleep

VLPO

32

gaba and galanin are inhbitiory transmitters with fibers proecting to

arousal centers (LC, PAG, LDT/PPT, DR, orexins)

33

during NREM, serotonin, norepeinhepine, dopamine all fire supressing ___ alloing the porcess of sleep stage 1-4

acetylcholine

34

adenosine build up inhbiits

wakefulness centers

35

adenosine homeostsis increases while awake during

metabolism

36

adenosine build up sitmulates

VLPO to cause sleep

37

Sleep drive ___ the longer one stays awake.

Q image thumb

increases

38

lack oflight via eyes/optic nerve signals the ___ of the hypothlamaus for mealtonin release

suprhciasmatic 

39

melatonin can be supressed with

24 hour light

40

CRY, CLOCK, BMAL1, PER1 are ___ genes

clock genes that control your circadian clock

A image thumb
41

___ drive transcription of cry/per/pev-erba

clock/bmal1

42

zeitgebers that modibfy our clock

melatonin, caffeine, alcohol

light

food

exercise

social interaction

43

 if I drank some coffee at 3pm, I would ____ my adenosine load and my brain would think it is noon allowing me to be less sleep.

lower

44

insomnia is defined as difficult inaitiating or maintain sleep, early morning awkaening, non restorative sleep for

1 month

45

sleep deprivation results in less activation in the

frontal lobe

46

narcolepsy ivnovles daily sleepa ttackes for

3 months

47

narcolepsy involves no ___ latency

rem

48

circadian rhytm sleep disorder yeilds __ or ___ due to sleep wake cycle mismatch, shift, or synchrony

insomnia or hypersomnia

49

___ circadian rhytm disorder involves falling asleep too early at night and waking too early

advanced

50

circadian rhythm sleep disorder should be tx with

sleep scheduling, benzos, melatonin, exercise, stimulants or light therapy

51

nocturnal myoclonus involves 

iunconcious leg movements

this is now called periodic limb movement disorder

52

___ involves concious leg movement and creeping sensations

restless legs

53

you remember dream with ___ disorder

nightmare

54

with nightmare disorder you awake

alert and oriented

55

with sleep terror disorder you awake

disorented, not consolable

56

sleep relatex bruxism is efined as

teeth grinding

57

REM sleep behavior disorder is defined as

loss of atonia during rem (acting out dreams)

often violent, men act out dreams sometimes

58

tx of REM sleep behavior disorder

d2 agonists