Sleep Disorders CC6 Flashcards Preview

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Flashcards in Sleep Disorders CC6 Deck (58)
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1
Q

what do you need to have to be dx with sleep disorder?

A

must have next day consequences

2
Q

what do you need to LACK to be dx with a sleep disorder

A

ANY organic, psych, or substance etiology

3
Q

advanced circadian clock problems often involves what population

A

elderly people go to sleep and wake up early

4
Q

delayed circadian clock problems often involves what population

A

third shift work, jet lag

5
Q

what should you tx insomnia with

A

GABA, galanine, or psychotherapy

6
Q

what should you tx hypersomnia with

A

stimulants, antidepressants, or naps

7
Q

which sleep disorder has the strongest genetic ties?

A

narcolepsy

8
Q

cause of narcelopsy

A

caused by autoimmune destruction of orexin (“backup generator”) neurons

9
Q

hypnopompic hallucinations

A

hallucinations upon waking

10
Q

hypnogogic hallucinations

A

hallucinations uponm sleeping

11
Q

what is cataplexy often triggered by

A

strong emotions

12
Q

central sleep apnea involves

A

the brainstem stops working in sleep

13
Q

Obstructive sleep apnea is associated with loss of ___

A

muscle tone

14
Q

obstructive sleep apnea is associated with

A

age, high BP, and obesity.

15
Q

tx for sleep apnea

A

central psotiive airway pressure or dental devices

16
Q

what is not recommended for tx for sleep apnea

A

surgery

17
Q

cause of Restless Legs Syndrome?

A

combination of genes and environment

18
Q

low Fe can be a cause of

A

restless legs syndrome

19
Q

tx of restless leg syndrome?

A

dopamine

20
Q

sleep terrors occur during

A

3/4 sleep

21
Q

nightmare disorder occurs during

A

rem sleep

22
Q

Sleepwalking/Somnambulism occurs during

A

stage 3/4 sleep

23
Q

sleep talking occurs during

A

all sleep stages

24
Q

Sleep Related Bruxism occurs during

A

stage 2 sleep

25
Q

the ___ areas of the alteral hypothlaamus are the off switchand NREM promoting center of the CNS

A

ventrolateral and median preoptic

26
Q

VLPO/MNPO causes us to sleep via increased

A

gaba and galanin activity

27
Q

VLPO/MNPO turns off ___ TMN wakefulness half of the switch

A

histamine

28
Q

VLPO/MNPO are silent during

A

wakelfulness

29
Q

when does VLPO/MNPO fire?

A

during NREM

30
Q

___ fires mostly as one drifts to sleep

A

MNPO

31
Q

___ fires while asleep

A

VLPO

32
Q

gaba and galanin are inhbitiory transmitters with fibers proecting to

A

arousal centers (LC, PAG, LDT/PPT, DR, orexins)

33
Q

during NREM, serotonin, norepeinhepine, dopamine all fire supressing ___ alloing the porcess of sleep stage 1-4

A

acetylcholine

34
Q

adenosine build up inhbiits

A

wakefulness centers

35
Q

adenosine homeostsis increases while awake during

A

metabolism

36
Q

adenosine build up sitmulates

A

VLPO to cause sleep

37
Q

Sleep drive ___ the longer one stays awake.

A

increases

38
Q

lack oflight via eyes/optic nerve signals the ___ of the hypothlamaus for mealtonin release

A

suprhciasmatic 

39
Q

melatonin can be supressed with

A

24 hour light

40
Q

CRY, CLOCK, BMAL1, PER1 are ___ genes

A

clock genes that control your circadian clock

41
Q

___ drive transcription of cry/per/pev-erba

A

clock/bmal1

42
Q

zeitgebers that modibfy our clock

A

melatonin, caffeine, alcohol

light

food

exercise

social interaction

43
Q

 if I drank some coffee at 3pm, I would ____ my adenosine load and my brain would think it is noon allowing me to be less sleep.

A

lower

44
Q

insomnia is defined as difficult inaitiating or maintain sleep, early morning awkaening, non restorative sleep for

A

1 month

45
Q

sleep deprivation results in less activation in the

A

frontal lobe

46
Q

narcolepsy ivnovles daily sleepa ttackes for

A

3 months

47
Q

narcolepsy involves no ___ latency

A

rem

48
Q

circadian rhytm sleep disorder yeilds __ or ___ due to sleep wake cycle mismatch, shift, or synchrony

A

insomnia or hypersomnia

49
Q

___ circadian rhytm disorder involves falling asleep too early at night and waking too early

A

advanced

50
Q

circadian rhythm sleep disorder should be tx with

A

sleep scheduling, benzos, melatonin, exercise, stimulants or light therapy

51
Q

nocturnal myoclonus involves 

A

iunconcious leg movements

this is now called periodic limb movement disorder

52
Q

___ involves concious leg movement and creeping sensations

A

restless legs

53
Q

you remember dream with ___ disorder

A

nightmare

54
Q

with nightmare disorder you awake

A

alert and oriented

55
Q

with sleep terror disorder you awake

A

disorented, not consolable

56
Q

sleep relatex bruxism is efined as

A

teeth grinding

57
Q

REM sleep behavior disorder is defined as

A

loss of atonia during rem (acting out dreams)

often violent, men act out dreams sometimes

58
Q

tx of REM sleep behavior disorder

A

d2 agonists