CNS degenerative disorders lecture #3 Flashcards Preview

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Flashcards in CNS degenerative disorders lecture #3 Deck (40):
1

What are they ways to manage dental needs in Alzheimer's disease pts?

-Provide short, simple instructions
-Use a "watch me" technique
-Monitor daily oral care
-Keep up with regular dental visits for as long as possible

2

What are the clinical manifestations of Multiple Sclerosis?

-Demyleination
-Site specific
-Progressive and relapsing/remission

3

What type of disease is MS?

-Demyelination disease leading to inflammation and scarring

4

T/F The symptoms of MS are site specific

True

5

What can MS effect?

-Senses
-Autonomics
-Cognition
-Depression
-Fatigue

6

What does heat and stress do to MS patients?

-Stimulate MS episodes

7

Where do you see most patients with MS?

-Places where Scandinavian populations have settled (In the US the northern states)

8

Is MS genetic?

-Yes

9

Is MS a male or female disease?

-More female

10

When do you start to see MS?

-Earlier in life than most other degenerative diseases

11

How may people in the US have MS?

-300,000

12

What are the initiating factors of MS?

-Possibly a viral infection
-It is an Autoimmune disease

13

What is the progression of MS like?

-It is variable from person to person with relapses/remissions

14

What are the four classifications of MS?

-Benign
-Relapsing remission
-Relapsing progressive
-Chronic progression

15

If you have Benign MS what symptoms are associated with it?

-Not really any symptoms except maybe some fatigue

16

If you have relapsing remission of MS what is associated with it?

-Symptoms Come and Go (on/off) but there is no worsening of the disease

17

If you have relapsing progressive of MS what is associated with it?

-Symptoms come and go but the severity of the disease continues to progress

18

If you have chronic progression of MS what is associated with it?

-It continually progresses once you start getting symptoms
-Usually fatal

19

Where does MS occur?

-In the brain

20

What is the diagnosis and treatment of MS?

-There is no definitive test to diagnose MS
-You can use MRIs to see opacities but that isn't the only thing that can appear opaque in the brain

21

When do they call is MS?

-If the brain scan has more than 2 areas of opacities
-And if you have the symptoms of MS

22

What do the symptoms of MS depend on?

-Where you see the opacities in the MRI

23

How do you manage relapses of MS?

-Prednisone (steroid for anti-inflammation)
-Interferon (Potent genetic approach to dealing with inflammation)
-Methyltrexate

24

If you have bowel dysfunction of MS what drug will you give?

-Metamucil (psyllium)

25

What symptoms are common with MS?

-Bladder dysfunction
-Bowel Dysfunction
-Depression
-Fatigue
-Pain
-Tremors

26

If you have bladder dysfunctions of MS what drug will you give?

-Tamsulosin (Flomax)

27

If you have depression with MS what drug will you give?

-Prozac

28

If you have fatigue with MS what drug will you give?

-Modafinil

29

If you have pain with MS what drug will you give?

-Gabapentin (Neurontin) (anti-seizure drug)

30

If you have tremors with MS what drug will you give?

-Clonazepam (Klonopin)

31

What does ALS stand for?

-Amyotrophic lateral schlerosis

32

What does ALS damage and do?

-CNS nerves that destroy voluntary skeletal muscles

33

What is a chronic autoimmune damage to skeletal muscles and diminished contact between neurons and skeletal muscles?

Myasthenia gravis

34

What causes Myasthenia Gravis?

-Nueromuscular junction
-Destroy receptors for acetylcholine

35

What drugs do you use for Myasthenia Gravis?

-Acetylcholinesterase inhibitor

36

If you stigmine what type of drug is it?

-Acetylcholinesterase inhibitor

37

What is a disorder in which the body's immune system attacks part of the peripheral nervous system?

-Guillain-Barrie syndrome

38

When does Guillain-Barre occur?

-A few days or weeks after the patient has had symptoms of a respiratory or GI viral infection

39

Extrapyramidal disease includes what groups of clinical disorders?

-Parkinsonism
-Chorea
-Athetosis

40

What is an extrapyramidal disease?

-It is a functional rather than anatomical unit problem marked by abnormal involuntary movements, alterations in muscle tone and postural disturbances

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